null

SMILES: CN(C)C\C=C\C(=O)N1CCC[C@H](C1)n1c(F)c(-c2ccc(Oc3ccccc3)cc2)c2c(N)n[nH]c(=O)c12

InChI Key: InChIKey=WKSYPRVFJQUJOR-WUTDNEBXSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 390069   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase BTK (Homo sapiens (Human))	BDBM390069 (US10323037, Example 82 | US9951077, 82) Show SMILES CN(C)C\C=C\C(=O)N1CCC[C@H](C1)n1c(F)c(-c2ccc(Oc3ccccc3)cc2)c2c(N)n[nH]c(=O)c12 Show InChI InChI=1S/C29H31FN6O3/c1-34(2)16-7-11-23(37)35-17-6-8-20(18-35)36-26-25(28(31)32-33-29(26)38)24(27(36)30)19-12-14-22(15-13-19)39-21-9-4-3-5-10-21/h3-5,7,9-15,20H,6,8,16-18H2,1-2H3,(H2,31,32)(H,33,38)/b11-7+/t20-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
JIANGSU HENGRUI MEDICINE CO., LTD. US Patent					Assay Description The Btk kinase assay was performed using a ADP-Glo Btk kinase assay kit purchased from Promega (Madison, Wis.). The assay was conducted according to ...				US Patent US10323037 (2019) BindingDB Entry DOI: 10.7270/Q2W098BW
					More data for this Ligand-Target Pair
Tyrosine-protein kinase BTK (Homo sapiens (Human))	BDBM390069 (US10323037, Example 82 | US9951077, 82) Show SMILES CN(C)C\C=C\C(=O)N1CCC[C@H](C1)n1c(F)c(-c2ccc(Oc3ccccc3)cc2)c2c(N)n[nH]c(=O)c12 Show InChI InChI=1S/C29H31FN6O3/c1-34(2)16-7-11-23(37)35-17-6-8-20(18-35)36-26-25(28(31)32-33-29(26)38)24(27(36)30)19-12-14-22(15-13-19)39-21-9-4-3-5-10-21/h3-5,7,9-15,20H,6,8,16-18H2,1-2H3,(H2,31,32)(H,33,38)/b11-7+/t20-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
GSK					Assay Description The Btk kinase assay was performed using a ADP-Glo Btk kinase assay kit purchased from Promega (Madison, Wis.). The assay was conducted according to ...				Bioorg Med Chem Lett 17: 3972-7 (2007) BindingDB Entry DOI: 10.7270/Q2MG7RV0
					More data for this Ligand-Target Pair