null

SMILES: Cn1cc(-c2cc(ccc2Oc2ccc(F)cc2F)S(C)(=O)=O)c2cc(CN3CCN(CC3)C3CCOCC3)[nH]c2c1=O

InChI Key: InChIKey=XVDGEDIPXWSYHY-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 390852   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM390852 (US9957263, Example 116) Show SMILES Cn1cc(-c2cc(ccc2Oc2ccc(F)cc2F)S(C)(=O)=O)c2cc(CN3CCN(CC3)C3CCOCC3)[nH]c2c1=O Show InChI InChI=1S/C31H34F2N4O5S/c1-35-19-26(24-17-23(43(2,39)40)4-6-28(24)42-29-5-3-20(32)15-27(29)33)25-16-21(34-30(25)31(35)38)18-36-9-11-37(12-10-36)22-7-13-41-14-8-22/h3-6,15-17,19,22,34H,7-14,18H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	3.33	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GSK					Assay Description Compound dilution series were prepared in DMSO via a 3-fold serial dilution from 2.5 mM to 42 nM. Compounds were then diluted 6:100 in assay buffer (...				Bioorg Med Chem Lett 19: 360-4 (2009) BindingDB Entry DOI: 10.7270/Q2Q81GDF
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM390852 (US9957263, Example 116) Show SMILES Cn1cc(-c2cc(ccc2Oc2ccc(F)cc2F)S(C)(=O)=O)c2cc(CN3CCN(CC3)C3CCOCC3)[nH]c2c1=O Show InChI InChI=1S/C31H34F2N4O5S/c1-35-19-26(24-17-23(43(2,39)40)4-6-28(24)42-29-5-3-20(32)15-27(29)33)25-16-21(34-30(25)31(35)38)18-36-9-11-37(12-10-36)22-7-13-41-14-8-22/h3-6,15-17,19,22,34H,7-14,18H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	98.4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GSK					Assay Description Compound dilution series were prepared in DMSO via a 3-fold serial dilution from 2.5 mM to 42 nM. Compounds were then diluted 6:100 in assay buffer (...				Bioorg Med Chem Lett 19: 360-4 (2009) BindingDB Entry DOI: 10.7270/Q2Q81GDF
					More data for this Ligand-Target Pair