null

SMILES: CC(NS(=O)(=O)c1ccc(-c2sc(nc2CC2CCCCC2)C(=O)NC2CCOCC2)c2ccccc12)C(F)(F)F

InChI Key: InChIKey=TXSZPTCXESKVKJ-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 392014   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Isoform 2 of Nuclear receptor ROR-gamma (RORgT) (Homo sapiens (Human))	BDBM392014 (US10301272, Example 6/12) Show SMILES CC(NS(=O)(=O)c1ccc(-c2sc(nc2CC2CCCCC2)C(=O)NC2CCOCC2)c2ccccc12)C(F)(F)F Show InChI InChI=1S/C29H34F3N3O4S2/c1-18(29(30,31)32)35-41(37,38)25-12-11-23(21-9-5-6-10-22(21)25)26-24(17-19-7-3-2-4-8-19)34-28(40-26)27(36)33-20-13-15-39-16-14-20/h5-6,9-12,18-20,35H,2-4,7-8,13-17H2,1H3,(H,33,36)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	126	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc.					Assay Description Determination of a ligand mediated Gal4 promoter driven transactivation to quantify ligand binding to RORγ was performed as follows: DNA encodin...				J Med Chem 52: 1814-27 (2009) BindingDB Entry DOI: 10.7270/Q2S184TJ
					More data for this Ligand-Target Pair
Isoform 2 of Nuclear receptor ROR-gamma (RORgT) (Homo sapiens (Human))	BDBM392014 (US10301272, Example 6/12) Show SMILES CC(NS(=O)(=O)c1ccc(-c2sc(nc2CC2CCCCC2)C(=O)NC2CCOCC2)c2ccccc12)C(F)(F)F Show InChI InChI=1S/C29H34F3N3O4S2/c1-18(29(30,31)32)35-41(37,38)25-12-11-23(21-9-5-6-10-22(21)25)26-24(17-19-7-3-2-4-8-19)34-28(40-26)27(36)33-20-13-15-39-16-14-20/h5-6,9-12,18-20,35H,2-4,7-8,13-17H2,1H3,(H,33,36)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc.					Assay Description Cells were incubated for additional 16 h before renilla (REN) luciferase activities were measured sequentially in the same cell extract using a Dual-...				J Med Chem 52: 1814-27 (2009) BindingDB Entry DOI: 10.7270/Q2S184TJ
					More data for this Ligand-Target Pair
Isoform 2 of Nuclear receptor ROR-gamma (RORgT) (Homo sapiens (Human))	BDBM392014 (US10301272, Example 6/12) Show SMILES CC(NS(=O)(=O)c1ccc(-c2sc(nc2CC2CCCCC2)C(=O)NC2CCOCC2)c2ccccc12)C(F)(F)F Show InChI InChI=1S/C29H34F3N3O4S2/c1-18(29(30,31)32)35-41(37,38)25-12-11-23(21-9-5-6-10-22(21)25)26-24(17-19-7-3-2-4-8-19)34-28(40-26)27(36)33-20-13-15-39-16-14-20/h5-6,9-12,18-20,35H,2-4,7-8,13-17H2,1H3,(H,33,36)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc.					Assay Description Cells were incubated for additional 16 h before firefly (FF) luciferase activities were measured sequentially in the same cell extract using a Dual-L...				J Med Chem 52: 1814-27 (2009) BindingDB Entry DOI: 10.7270/Q2S184TJ
					More data for this Ligand-Target Pair