BindingDB logo
myBDB logout

BDBM392676 US10301286, Example 45

SMILES: COc1ccc(cc1)C1CN(CC1C(=O)N1CCN(C[C@@H]1C)[C@@H](Cc1ccc2CCCc2c1)C(O)=O)C(C)(C)C

InChI Key: InChIKey=OAYNPVHORKQFBZ-BBXBJHCUSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 392676   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Melanocortin receptor 4


(Homo sapiens (Human))		BDBM392676
PNG
(US10301286, Example 45)
Show SMILES COc1ccc(cc1)C1CN(CC1C(=O)N1CCN(C[C@@H]1C)[C@@H](Cc1ccc2CCCc2c1)C(O)=O)C(C)(C)C |r|
Show InChI InChI=1S/C33H45N3O4/c1-22-19-34(30(32(38)39)18-23-9-10-24-7-6-8-26(24)17-23)15-16-36(22)31(37)29-21-35(33(2,3)4)20-28(29)25-11-13-27(40-5)14-12-25/h9-14,17,22,28-30H,6-8,15-16,18-21H2,1-5H3,(H,38,39)/t22-,28?,29?,30-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 1.10E+3n/an/an/an/a



GSK



Assay Description
Experiment Method(1) Construction of Human MC Receptor-Expressing VectorA human MC4 receptor gene (GenBank Accession No.: NM_005912.2), a human MC1 r...

Bioorg Med Chem Lett 19: 1332-6 (2009)


BindingDB Entry DOI: 10.7270/Q2833VCJ
More data for this
Ligand-Target Pair