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SMILES: CN(CCO)c1cc(-c2cnc3OCCCc3c2)c2nc[nH]c2c1C(N)=O

InChI Key: InChIKey=WWSYISJQXTYUKR-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 392783   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Putative glyoxylate/hydroxypyruvate reductase B (Staphylococcus aureus (strain SA113))	BDBM392783 (7-(3,4-Dihydro-2H-pyrano[2,3-b]pyridin-6-yl)-5-[(2...) Show SMILES CN(CCO)c1cc(-c2cnc3OCCCc3c2)c2nc[nH]c2c1C(N)=O Show InChI InChI=1S/C19H21N5O3/c1-24(4-5-25)14-8-13(16-17(23-10-22-16)15(14)18(20)26)12-7-11-3-2-6-27-19(11)21-9-12/h7-10,25H,2-6H2,1H3,(H2,20,26)(H,22,23)	MMDB NCI pathway Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
GSK					Assay Description The assay buffer “AB” contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The followi...				Bioorg Med Chem Lett 18: 5018-22 (2008) BindingDB Entry DOI: 10.7270/Q2R213Q5
					More data for this Ligand-Target Pair
D-alanine--D-alanyl carrier protein ligase (Streptococcus agalactiae serotype V (strain ATCC B...)	BDBM392783 (7-(3,4-Dihydro-2H-pyrano[2,3-b]pyridin-6-yl)-5-[(2...) Show SMILES CN(CCO)c1cc(-c2cnc3OCCCc3c2)c2nc[nH]c2c1C(N)=O Show InChI InChI=1S/C19H21N5O3/c1-24(4-5-25)14-8-13(16-17(23-10-22-16)15(14)18(20)26)12-7-11-3-2-6-27-19(11)21-9-12/h7-10,25H,2-6H2,1H3,(H2,20,26)(H,22,23)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
GSK					Assay Description The assay buffer “AB” contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The followi...				Bioorg Med Chem Lett 18: 5018-22 (2008) BindingDB Entry DOI: 10.7270/Q2R213Q5
					More data for this Ligand-Target Pair
D-alanine--D-alanyl carrier protein ligase (Enterococcus faecium E1679)	BDBM392783 (7-(3,4-Dihydro-2H-pyrano[2,3-b]pyridin-6-yl)-5-[(2...) Show SMILES CN(CCO)c1cc(-c2cnc3OCCCc3c2)c2nc[nH]c2c1C(N)=O Show InChI InChI=1S/C19H21N5O3/c1-24(4-5-25)14-8-13(16-17(23-10-22-16)15(14)18(20)26)12-7-11-3-2-6-27-19(11)21-9-12/h7-10,25H,2-6H2,1H3,(H2,20,26)(H,22,23)	MMDB NCI pathway Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	320	n/a	n/a	n/a	n/a	n/a	n/a
GSK					Assay Description The assay buffer “AB” contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The followi...				Bioorg Med Chem Lett 18: 5018-22 (2008) BindingDB Entry DOI: 10.7270/Q2R213Q5
					More data for this Ligand-Target Pair
D-alanine--D-alanyl carrier protein ligase (Enterococcus faecalis (strain ATCC 700802 / V583))	BDBM392783 (7-(3,4-Dihydro-2H-pyrano[2,3-b]pyridin-6-yl)-5-[(2...) Show SMILES CN(CCO)c1cc(-c2cnc3OCCCc3c2)c2nc[nH]c2c1C(N)=O Show InChI InChI=1S/C19H21N5O3/c1-24(4-5-25)14-8-13(16-17(23-10-22-16)15(14)18(20)26)12-7-11-3-2-6-27-19(11)21-9-12/h7-10,25H,2-6H2,1H3,(H2,20,26)(H,22,23)	MMDB KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	45	n/a	n/a	n/a	n/a	n/a	n/a
GSK					Assay Description The assay buffer “AB” contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The followi...				Bioorg Med Chem Lett 18: 5018-22 (2008) BindingDB Entry DOI: 10.7270/Q2R213Q5
					More data for this Ligand-Target Pair