BDBM392791 5-[2-(dimethylamino)ethyl-methyl-amino]-7-[6-(dimethylamino)-3-pyridyl]-3H-benzimidazole-4-carboxamide::US10301305, Example 205

SMILES: CN(C)CCN(C)c1cc(-c2ccc(nc2)N(C)C)c2nc[nH]c2c1C(N)=O

InChI Key: InChIKey=LQSXOZDBYGXRQD-UHFFFAOYSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 392791   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D-alanine--D-alanyl carrier protein ligase (Staphylococcus aureus (strain SA113))	BDBM392791 (5-[2-(dimethylamino)ethyl-methyl-amino]-7-[6-(dime...) Show SMILES CN(C)CCN(C)c1cc(-c2ccc(nc2)N(C)C)c2nc[nH]c2c1C(N)=O Show InChI InChI=1S/C20H27N7O/c1-25(2)8-9-27(5)15-10-14(13-6-7-16(22-11-13)26(3)4)18-19(24-12-23-18)17(15)20(21)28/h6-7,10-12H,8-9H2,1-5H3,(H2,21,28)(H,23,24)	MMDB NCI pathway Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	n/a
GSK					Assay Description The assay buffer “AB” contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The followi...				Bioorg Med Chem Lett 18: 5018-22 (2008) BindingDB Entry DOI: 10.7270/Q2R213Q5
					More data for this Ligand-Target Pair
D-alanine--D-alanyl carrier protein ligase (Streptococcus agalactiae serotype V (strain ATCC B...)	BDBM392791 (5-[2-(dimethylamino)ethyl-methyl-amino]-7-[6-(dime...) Show SMILES CN(C)CCN(C)c1cc(-c2ccc(nc2)N(C)C)c2nc[nH]c2c1C(N)=O Show InChI InChI=1S/C20H27N7O/c1-25(2)8-9-27(5)15-10-14(13-6-7-16(22-11-13)26(3)4)18-19(24-12-23-18)17(15)20(21)28/h6-7,10-12H,8-9H2,1-5H3,(H2,21,28)(H,23,24)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
GSK					Assay Description The assay buffer “AB” contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The followi...				Bioorg Med Chem Lett 18: 5018-22 (2008) BindingDB Entry DOI: 10.7270/Q2R213Q5
					More data for this Ligand-Target Pair
D-alanine--D-alanyl carrier protein ligase (Enterococcus faecium E1679)	BDBM392791 (5-[2-(dimethylamino)ethyl-methyl-amino]-7-[6-(dime...) Show SMILES CN(C)CCN(C)c1cc(-c2ccc(nc2)N(C)C)c2nc[nH]c2c1C(N)=O Show InChI InChI=1S/C20H27N7O/c1-25(2)8-9-27(5)15-10-14(13-6-7-16(22-11-13)26(3)4)18-19(24-12-23-18)17(15)20(21)28/h6-7,10-12H,8-9H2,1-5H3,(H2,21,28)(H,23,24)	MMDB NCI pathway Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
GSK					Assay Description The assay buffer “AB” contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The followi...				Bioorg Med Chem Lett 18: 5018-22 (2008) BindingDB Entry DOI: 10.7270/Q2R213Q5
					More data for this Ligand-Target Pair
D-alanine--D-alanyl carrier protein ligase (Enterococcus faecalis (strain ATCC 700802 / V583))	BDBM392791 (5-[2-(dimethylamino)ethyl-methyl-amino]-7-[6-(dime...) Show SMILES CN(C)CCN(C)c1cc(-c2ccc(nc2)N(C)C)c2nc[nH]c2c1C(N)=O Show InChI InChI=1S/C20H27N7O/c1-25(2)8-9-27(5)15-10-14(13-6-7-16(22-11-13)26(3)4)18-19(24-12-23-18)17(15)20(21)28/h6-7,10-12H,8-9H2,1-5H3,(H2,21,28)(H,23,24)	MMDB KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	9.20	n/a	n/a	n/a	n/a	n/a	n/a
GSK					Assay Description The assay buffer “AB” contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The followi...				Bioorg Med Chem Lett 18: 5018-22 (2008) BindingDB Entry DOI: 10.7270/Q2R213Q5
					More data for this Ligand-Target Pair