BDBM392880 US10301306, Example 78

SMILES: Fc1ccc(cc1)-c1c2c(CCNC2=O)n(CC2CCCC2)c1-c1ccncc1

InChI Key: InChIKey=CASSLJRJRVDHKH-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 392880   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Receptor-interacting serine/threonine-protein kinase 3 (Homo sapiens (Human))	BDBM392880 (US10301306, Example 78) Show SMILES Fc1ccc(cc1)-c1c2c(CCNC2=O)n(CC2CCCC2)c1-c1ccncc1 Show InChI InChI=1S/C24H24FN3O/c25-19-7-5-17(6-8-19)21-22-20(11-14-27-24(22)29)28(15-16-3-1-2-4-16)23(21)18-9-12-26-13-10-18/h5-10,12-13,16H,1-4,11,14-15H2,(H,27,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<30	n/a	n/a	n/a	n/a	n/a	n/a
GSK					Assay Description The assays were performed in black 1536-well plates. The final assay volume of 2 μl contained a mixture of a fluorescently labeled HTRF probe, T...				Bioorg Med Chem Lett 18: 5018-22 (2008) BindingDB Entry DOI: 10.7270/Q2M90C19
					More data for this Ligand-Target Pair