BDBM394395 1-[5-(2,4-Difluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrol-3-yl]-N-methylmethanamine::US10308605, Example 225
SMILES: CNCc1cc(-c2ccc(F)cc2F)n(c1)S(=O)(=O)c1cccnc1
InChI Key: InChIKey=MEKCOJNXUWQYBP-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Potassium-transporting ATPase alpha chain 1 (Sus scrofa (Pig)) | BDBM394395 (1-[5-(2,4-Difluorophenyl)-1-(pyridin-3-ylsulfonyl)...) | PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 8.90 | n/a | n/a | n/a | n/a | n/a | n/a |
Washington University | Assay Description According to the method [Biochem. Biophys. Acta., 728, 31 (1983)] of Wallmark et al., a gastric mucous membrane microsomal fraction was prepared from... | J Med Chem 52: 2188-91 (2009) BindingDB Entry DOI: 10.7270/Q2FF3VPK | |||||||||||
More data for this Ligand-Target Pair |