BDBM394456 2-(6-amino-5-(3-::US10308614, Example 57

SMILES: Nc1nnc(cc1N1CC(C1)Oc1ccccc1)-c1ccccc1O

InChI Key: InChIKey=SFMYKATXFFQSND-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 394456   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transcription activator BRG1 [1448-1575] (Homo sapiens (Human))	BDBM394456 (2-(6-amino-5-(3- | US10308614, Example 57) Show SMILES Nc1nnc(cc1N1CC(C1)Oc1ccccc1)-c1ccccc1O Show InChI InChI=1S/C19H18N4O2/c20-19-17(10-16(21-22-19)15-8-4-5-9-18(15)24)23-11-14(12-23)25-13-6-2-1-3-7-13/h1-10,14,24H,11-12H2,(H2,20,22)	PDB MMDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	17.7	n/a	n/a	n/a	n/a	n/a	n/a
The Institute of Cancer Research					Assay Description His-BRG1 (A1448-S1575; Swiss Prot P51532; mhhhhhhgslvpr\gsAEKLSPNPP NLTKKMKKIVDAVIKYKDSSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNH KYRSLNDLEKDVMLLCQNA...				J Med Chem 52: 2255-64 (2009) BindingDB Entry DOI: 10.7270/Q26112NJ
					More data for this Ligand-Target Pair
Protein polybromo-1 [645-766] (Homo sapiens (Human))	BDBM394456 (2-(6-amino-5-(3- | US10308614, Example 57) Show SMILES Nc1nnc(cc1N1CC(C1)Oc1ccccc1)-c1ccccc1O Show InChI InChI=1S/C19H18N4O2/c20-19-17(10-16(21-22-19)15-8-4-5-9-18(15)24)23-11-14(12-23)25-13-6-2-1-3-7-13/h1-10,14,24H,11-12H2,(H2,20,22)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	13.3	n/a	n/a	n/a	n/a	n/a	n/a
The Institute of Cancer Research					Assay Description Histidine-Flag-PB1-BD5 Bromodomain645-766 (S645-D766; Swiss Prot Q86U86; mhhhhhhasdykddddkgslvpr\gsSGISPKKSKYMTPMQQKLNEVYEAVKNYTDKRGRRLSAI FLRLPSRSEL...				J Med Chem 52: 2255-64 (2009) BindingDB Entry DOI: 10.7270/Q26112NJ
					More data for this Ligand-Target Pair
Isoform Short of Probable global transcription activator SNF2L2 (Short) 377-1486] (Homo sapiens (Human))	BDBM394456 (2-(6-amino-5-(3- | US10308614, Example 57) Show SMILES Nc1nnc(cc1N1CC(C1)Oc1ccccc1)-c1ccccc1O Show InChI InChI=1S/C19H18N4O2/c20-19-17(10-16(21-22-19)15-8-4-5-9-18(15)24)23-11-14(12-23)25-13-6-2-1-3-7-13/h1-10,14,24H,11-12H2,(H2,20,22)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	35.6	n/a	n/a	n/a	n/a	n/a	n/a
The Institute of Cancer Research					Assay Description Histidine epitope tagged BRM (Isoform 2) Bromodomain1377-1486 (S1377-Q1486; Swiss Prot P51531-2; mhhhhhhgslvpr\gsSPNPPKLTKQMNAIIDTVINYKDSSGRQLSEVFIQL...				J Med Chem 52: 2255-64 (2009) BindingDB Entry DOI: 10.7270/Q26112NJ
					More data for this Ligand-Target Pair