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SMILES: Nc1nnc(cc1N1CC2CCC(C1)N2c1ccccc1)-c1ccccc1O

InChI Key: InChIKey=HRUFTLXIFIAYKI-UHFFFAOYSA-N

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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 394462   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Transcription activator BRG1 [1448-1575]


(Homo sapiens (Human))		BDBM394462
PNG
(2-(6-amino-5-(8-phenyl-3,8- | US10308614, Example ...)
Show SMILES Nc1nnc(cc1N1CC2CCC(C1)N2c1ccccc1)-c1ccccc1O |TLB:15:14:7.8.13:10.11|
Show InChI InChI=1S/C22H23N5O/c23-22-20(12-19(24-25-22)18-8-4-5-9-21(18)28)26-13-16-10-11-17(14-26)27(16)15-6-2-1-3-7-15/h1-9,12,16-17,28H,10-11,13-14H2,(H2,23,25)
PDB
MMDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 4.30n/an/an/an/an/an/a



The Institute of Cancer Research



Assay Description
His-BRG1 (A1448-S1575; Swiss Prot P51532; mhhhhhhgslvpr\gsAEKLSPNPP NLTKKMKKIVDAVIKYKDSSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNH KYRSLNDLEKDVMLLCQNA...

J Med Chem 52: 2255-64 (2009)


BindingDB Entry DOI: 10.7270/Q26112NJ
More data for this
Ligand-Target Pair