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SMILES: CN(C)CCOc1cc(nnc1N)-c1ccccc1O

InChI Key: InChIKey=SIWZRTOJDAJYHG-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 394570   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transcription activator BRG1 [1448-1575] (Homo sapiens (Human))	BDBM394570 (2-(6-amino-5-(2- | US10308614, Example 173) Show SMILES CN(C)CCOc1cc(nnc1N)-c1ccccc1O Show InChI InChI=1S/C14H18N4O2/c1-18(2)7-8-20-13-9-11(16-17-14(13)15)10-5-3-4-6-12(10)19/h3-6,9,19H,7-8H2,1-2H3,(H2,15,17)	PDB MMDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	263	n/a	n/a	n/a	n/a	n/a	n/a
The Institute of Cancer Research					Assay Description His-BRG1 (A1448-S1575; Swiss Prot P51532; mhhhhhhgslvpr\gsAEKLSPNPP NLTKKMKKIVDAVIKYKDSSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNH KYRSLNDLEKDVMLLCQNA...				J Med Chem 52: 2255-64 (2009) BindingDB Entry DOI: 10.7270/Q26112NJ
					More data for this Ligand-Target Pair
Protein polybromo-1 [645-766] (Homo sapiens (Human))	BDBM394570 (2-(6-amino-5-(2- | US10308614, Example 173) Show SMILES CN(C)CCOc1cc(nnc1N)-c1ccccc1O Show InChI InChI=1S/C14H18N4O2/c1-18(2)7-8-20-13-9-11(16-17-14(13)15)10-5-3-4-6-12(10)19/h3-6,9,19H,7-8H2,1-2H3,(H2,15,17)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	257	n/a	n/a	n/a	n/a	n/a	n/a
The Institute of Cancer Research					Assay Description Histidine-Flag-PB1-BD5 Bromodomain645-766 (S645-D766; Swiss Prot Q86U86; mhhhhhhasdykddddkgslvpr\gsSGISPKKSKYMTPMQQKLNEVYEAVKNYTDKRGRRLSAI FLRLPSRSEL...				J Med Chem 52: 2255-64 (2009) BindingDB Entry DOI: 10.7270/Q26112NJ
					More data for this Ligand-Target Pair
Isoform Short of Probable global transcription activator SNF2L2 (Short) 377-1486] (Homo sapiens (Human))	BDBM394570 (2-(6-amino-5-(2- | US10308614, Example 173) Show SMILES CN(C)CCOc1cc(nnc1N)-c1ccccc1O Show InChI InChI=1S/C14H18N4O2/c1-18(2)7-8-20-13-9-11(16-17-14(13)15)10-5-3-4-6-12(10)19/h3-6,9,19H,7-8H2,1-2H3,(H2,15,17)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	276	n/a	n/a	n/a	n/a	n/a	n/a
The Institute of Cancer Research					Assay Description Histidine epitope tagged BRM (Isoform 2) Bromodomain1377-1486 (S1377-Q1486; Swiss Prot P51531-2; mhhhhhhgslvpr\gsSPNPPKLTKQMNAIIDTVINYKDSSGRQLSEVFIQL...				J Med Chem 52: 2255-64 (2009) BindingDB Entry DOI: 10.7270/Q26112NJ
					More data for this Ligand-Target Pair