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SMILES: C[C@H]1CN(CCN1c1ccc(cn1)-c1nc(c[nH]1)C#N)c1ccc(C)c(F)c1

InChI Key:

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 395350   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Diacylglycerol O-acyltransferase 1


(Homo sapiens (Human))		BDBM395350
PNG
(US10308636, Example 37-6)
Show SMILES C[C@H]1CN(CCN1c1ccc(cn1)-c1nc(c[nH]1)C#N)c1ccc(C)c(F)c1 |r|
PDB

UniProtKB/SwissProt

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US Patent
n/an/a 21n/an/an/an/an/an/a



Wyeth Research



Assay Description
As a buffer used for the enzymatic reaction of DGAT1, 100 mM Tris-HCl (pH7.4), 200 mM Sucrose, and 20 mM MgCl2, 0.125% Bovin Serum Albumin (BSA) were...

Bioorg Med Chem Lett 19: 3485-8 (2009)


BindingDB Entry DOI: 10.7270/Q28S4S76
More data for this
Ligand-Target Pair