BDBM396164 6-(6-Amino-5-thiazol-5-yl-pyridin-2-ylmethyl)-5-methyl-[1,2,5]oxadiazolo[3,4-b]pyridin-7-ylamine::US10308667, Example 67

SMILES: Cc1nc2nonc2c(N)c1Cc1ccc(-c2cncs2)c(N)n1

InChI Key: InChIKey=JTZAMBMPSIKQQA-UHFFFAOYSA-N

Data: 1 IC50

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 396164   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ghrelin O-acyltransferase (Homo sapiens (Human))	BDBM396164 (6-(6-Amino-5-thiazol-5-yl-pyridin-2-ylmethyl)-5-me...) Show SMILES Cc1nc2nonc2c(N)c1Cc1ccc(-c2cncs2)c(N)n1 Show InChI InChI=1S/C15H13N7OS/c1-7-10(12(16)13-15(19-7)22-23-21-13)4-8-2-3-9(14(17)20-8)11-5-18-6-24-11/h2-3,5-6H,4,16H2,1H3,(H2,17,20)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.0500	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc.					Assay Description Cells are plated with a density of 5000 cells/well in 384-well poly-D-lysin plates and incubated for 1 day at 37° C., 5% CO2 in DMEM medium, 10% FCS,...				Bioorg Med Chem Lett 17: 4664-9 (2007) BindingDB Entry DOI: 10.7270/Q2VH5R5S
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