BDBM396167 6-(7-Amino-5-methyl-[1,2,5]oxadiazolo[3,4-b]pyridin-6-ylmethyl)-3-difluoromethoxy-pyridine-2-carbonitrile::US10308667, Example 70

SMILES: Cc1nc2nonc2c(N)c1Cc1ccc(OC(F)F)c(n1)C#N

InChI Key: InChIKey=YSIRVXKYVWQVRB-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 396167   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ghrelin O-acyltransferase (Homo sapiens (Human))	BDBM396167 (6-(7-Amino-5-methyl-[1,2,5]oxadiazolo[3,4-b]pyridi...) Show SMILES Cc1nc2nonc2c(N)c1Cc1ccc(OC(F)F)c(n1)C#N Show InChI InChI=1S/C14H10F2N6O2/c1-6-8(11(18)12-13(19-6)22-24-21-12)4-7-2-3-10(23-14(15)16)9(5-17)20-7/h2-3,14H,4,18H2,1H3	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.0820	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc.					Assay Description Cells are plated with a density of 5000 cells/well in 384-well poly-D-lysin plates and incubated for 1 day at 37° C., 5% CO2 in DMEM medium, 10% FCS,...				Bioorg Med Chem Lett 17: 4664-9 (2007) BindingDB Entry DOI: 10.7270/Q2VH5R5S
					More data for this Ligand-Target Pair