BDBM396180 6-[5-bromo-4-(trifluoromethyl)pyrimidin-2-yl]methyl-5-methyl-[1,2,5]oxadiazolo[3,4-b]pyridin-7-amine::US10308667, Example 83

SMILES: Cc1nc2nonc2c(N)c1Cc1ncc(Br)c(n1)C(F)(F)F

InChI Key: InChIKey=VSEZRZDYPSIBFX-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 396180   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ghrelin O-acyltransferase (Homo sapiens (Human))	BDBM396180 (6-[5-bromo-4-(trifluoromethyl)pyrimidin-2-yl]methy...) Show SMILES Cc1nc2nonc2c(N)c1Cc1ncc(Br)c(n1)C(F)(F)F Show InChI InChI=1S/C12H8BrF3N6O/c1-4-5(8(17)9-11(19-4)22-23-21-9)2-7-18-3-6(13)10(20-7)12(14,15)16/h3H,2,17H2,1H3	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.0770	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc.					Assay Description Cells are plated with a density of 5000 cells/well in 384-well poly-D-lysin plates and incubated for 1 day at 37° C., 5% CO2 in DMEM medium, 10% FCS,...				Bioorg Med Chem Lett 17: 4664-9 (2007) BindingDB Entry DOI: 10.7270/Q2VH5R5S
					More data for this Ligand-Target Pair