BDBM396192 6-[5-Bromo-6-(3-methyl-oxetan-3-ylmethoxy)-pyridin-2-ylmethyl]-5-methyl-[1,2,5]oxadiazolo[3,4-b]pyridin-7-ylamine::US10308667, Example 95

SMILES: Cc1nc2nonc2c(N)c1Cc1ccc(Br)c(OCC2(C)COC2)n1

InChI Key: InChIKey=NJZXOZCIOINNKA-UHFFFAOYSA-N

Data: 1 IC50

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 396192   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ghrelin O-acyltransferase (Homo sapiens (Human))	BDBM396192 (6-[5-Bromo-6-(3-methyl-oxetan-3-ylmethoxy)-pyridin...) Show SMILES Cc1nc2nonc2c(N)c1Cc1ccc(Br)c(OCC2(C)COC2)n1 Show InChI InChI=1S/C17H18BrN5O3/c1-9-11(13(19)14-15(20-9)23-26-22-14)5-10-3-4-12(18)16(21-10)25-8-17(2)6-24-7-17/h3-4H,5-8,19H2,1-2H3	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.0820	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc.					Assay Description Cells are plated with a density of 5000 cells/well in 384-well poly-D-lysin plates and incubated for 1 day at 37° C., 5% CO2 in DMEM medium, 10% FCS,...				Bioorg Med Chem Lett 17: 4664-9 (2007) BindingDB Entry DOI: 10.7270/Q2VH5R5S
					More data for this Ligand-Target Pair