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SMILES: Cc1nc2nonc2c(N)c1Cc1ccc(C#N)c(OCCCF)n1

InChI Key: InChIKey=HCBYRROPYSAWTC-UHFFFAOYSA-N

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 396205   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Ghrelin O-acyltransferase


(Homo sapiens (Human))		BDBM396205
PNG
(6-(7-Amino-5-methyl-[1,2,5]oxadiazolo[3,4-b]pyridi...)
Show SMILES Cc1nc2nonc2c(N)c1Cc1ccc(C#N)c(OCCCF)n1
Show InChI InChI=1S/C16H15FN6O2/c1-9-12(13(19)14-15(20-9)23-25-22-14)7-11-4-3-10(8-18)16(21-11)24-6-2-5-17/h3-4H,2,5-7,19H2,1H3
UniProtKB/SwissProt

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PC cid
PC sid
UniChem
US Patent
n/an/a 0.0260n/an/an/an/an/an/a



Boehringer Ingelheim Pharmaceuticals Inc.



Assay Description
Cells are plated with a density of 5000 cells/well in 384-well poly-D-lysin plates and incubated for 1 day at 37° C., 5% CO2 in DMEM medium, 10% FCS,...

Bioorg Med Chem Lett 17: 4664-9 (2007)


BindingDB Entry DOI: 10.7270/Q2VH5R5S
More data for this
Ligand-Target Pair