BDBM396216 6-(6-Amino-5-difluoromethoxy-pyridin-2-ylmethyl)-5-methyl-[1,2,5]oxadiazolo[3,4-b]pyridin-7-ylamine::US10308667, Example 119

SMILES: Cc1nc2nonc2c(N)c1Cc1ccc(OC(F)F)c(N)n1

InChI Key: InChIKey=KJXBASFBIGYRBH-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 396216   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ghrelin O-acyltransferase (Homo sapiens (Human))	BDBM396216 (6-(6-Amino-5-difluoromethoxy-pyridin-2-ylmethyl)-5...) Show SMILES Cc1nc2nonc2c(N)c1Cc1ccc(OC(F)F)c(N)n1 Show InChI InChI=1S/C13H12F2N6O2/c1-5-7(9(16)10-12(18-5)21-23-20-10)4-6-2-3-8(11(17)19-6)22-13(14)15/h2-3,13H,4,16H2,1H3,(H2,17,19)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.0910	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc.					Assay Description Cells are plated with a density of 5000 cells/well in 384-well poly-D-lysin plates and incubated for 1 day at 37° C., 5% CO2 in DMEM medium, 10% FCS,...				Bioorg Med Chem Lett 17: 4664-9 (2007) BindingDB Entry DOI: 10.7270/Q2VH5R5S
					More data for this Ligand-Target Pair