BDBM396219 1-[6-(7-Amino-5-methyl-[1,2,5]oxadiazolo[3,4-b]pyridin-6-ylmethyl)-3-bromo-pyridin-2-yl]-3-methyl-azetidin-3-ol::US10308667, Example 122

SMILES: Cc1nc2nonc2c(N)c1Cc1ccc(Br)c(n1)N1CC(C)(O)C1

InChI Key: InChIKey=VXIZUPKBUIVDSC-UHFFFAOYSA-N

Data: 1 IC50

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 396219   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ghrelin O-acyltransferase (Homo sapiens (Human))	BDBM396219 (1-[6-(7-Amino-5-methyl-[1,2,5]oxadiazolo[3,4-b]pyr...) Show SMILES Cc1nc2nonc2c(N)c1Cc1ccc(Br)c(n1)N1CC(C)(O)C1 Show InChI InChI=1S/C16H17BrN6O2/c1-8-10(12(18)13-14(19-8)22-25-21-13)5-9-3-4-11(17)15(20-9)23-6-16(2,24)7-23/h3-4,24H,5-7,18H2,1-2H3	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.0330	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc.					Assay Description Cells are plated with a density of 5000 cells/well in 384-well poly-D-lysin plates and incubated for 1 day at 37° C., 5% CO2 in DMEM medium, 10% FCS,...				Bioorg Med Chem Lett 17: 4664-9 (2007) BindingDB Entry DOI: 10.7270/Q2VH5R5S
					More data for this Ligand-Target Pair