BDBM396222 6-(5-Bromo-6-cyclopropylamino-pyridin-2-ylmethyl)-5-methyl-[1,2,5]oxadiazolo[3,4-b]pyridin-7-ylamine::US10308667, Example 125

SMILES: Cc1nc2nonc2c(N)c1Cc1ccc(Br)c(NC2CC2)n1

InChI Key: InChIKey=WCXMBPQFHNVYPZ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 396222   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ghrelin O-acyltransferase (Homo sapiens (Human))	BDBM396222 (6-(5-Bromo-6-cyclopropylamino-pyridin-2-ylmethyl)-...) Show SMILES Cc1nc2nonc2c(N)c1Cc1ccc(Br)c(NC2CC2)n1 Show InChI InChI=1S/C15H15BrN6O/c1-7-10(12(17)13-15(18-7)22-23-21-13)6-9-4-5-11(16)14(20-9)19-8-2-3-8/h4-5,8H,2-3,6,17H2,1H3,(H,19,20)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.0380	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc.					Assay Description Cells are plated with a density of 5000 cells/well in 384-well poly-D-lysin plates and incubated for 1 day at 37° C., 5% CO2 in DMEM medium, 10% FCS,...				Bioorg Med Chem Lett 17: 4664-9 (2007) BindingDB Entry DOI: 10.7270/Q2VH5R5S
					More data for this Ligand-Target Pair