BDBM396224 3-[6-(7-Amino-5-methyl-[1,2,5]oxadiazolo[3,4-b]pyridin-6-ylmethyl)-3-bromo-pyridin-2-ylamino]-2,2-di methyl-propionitrile::US10308667, Example 127

SMILES: Cc1nc2nonc2c(N)c1Cc1ccc(Br)c(NCC(C)(C)C#N)n1

InChI Key: InChIKey=SOTDIFYSAPNBGE-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 396224   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ghrelin O-acyltransferase (Homo sapiens (Human))	BDBM396224 (3-[6-(7-Amino-5-methyl-[1,2,5]oxadiazolo[3,4-b]pyr...) Show SMILES Cc1nc2nonc2c(N)c1Cc1ccc(Br)c(NCC(C)(C)C#N)n1 Show InChI InChI=1S/C17H18BrN7O/c1-9-11(13(20)14-16(22-9)25-26-24-14)6-10-4-5-12(18)15(23-10)21-8-17(2,3)7-19/h4-5H,6,8,20H2,1-3H3,(H,21,23)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.100	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc.					Assay Description Cells are plated with a density of 5000 cells/well in 384-well poly-D-lysin plates and incubated for 1 day at 37° C., 5% CO2 in DMEM medium, 10% FCS,...				Bioorg Med Chem Lett 17: 4664-9 (2007) BindingDB Entry DOI: 10.7270/Q2VH5R5S
					More data for this Ligand-Target Pair
Ghrelin O-acyltransferase (Homo sapiens (Human))	BDBM396224 (3-[6-(7-Amino-5-methyl-[1,2,5]oxadiazolo[3,4-b]pyr...) Show SMILES Cc1nc2nonc2c(N)c1Cc1ccc(Br)c(NCC(C)(C)C#N)n1 Show InChI InChI=1S/C17H18BrN7O/c1-9-11(13(20)14-16(22-9)25-26-24-14)6-10-4-5-12(18)15(23-10)21-8-17(2,3)7-19/h4-5H,6,8,20H2,1-3H3,(H,21,23)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.100	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc.					Assay Description Cells are plated with a density of 5000 cells/well in 384-well poly-D-lysin plates and incubated for 1 day at 37° C., 5% CO2 in DMEM medium, 10% FCS,...				Bioorg Med Chem Lett 17: 4664-9 (2007) BindingDB Entry DOI: 10.7270/Q2VH5R5S
					More data for this Ligand-Target Pair