BDBM396273 US10314827, Compound 22

SMILES: C[C@@H]1[C@H]2[C@@H](C[C@H](C)CN2CCN(C)C(C)=O)O[C@]11CC[C@H]2[C@@H]3CC[C@@H]4CC(=O)CC[C@]4(C)[C@H]3CC2=C(C)C1

InChI Key: InChIKey=LXTSDCHNKFDVDB-ZBIRBYKESA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 396273   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Alkaline phosphatase, germ cell type (Homo sapiens (Human))	BDBM396273 (US10314827, Compound 22) Show SMILES C[C@@H]1[C@H]2[C@@H](C[C@H](C)CN2CCN(C)C(C)=O)O[C@]11CC[C@H]2[C@@H]3CC[C@@H]4CC(=O)CC[C@]4(C)[C@H]3CC2=C(C)C1 |r,t:39| Show InChI InChI=1S/C33H52N2O3/c1-20-15-30-31(35(19-20)14-13-34(6)23(4)36)22(3)33(38-30)12-10-26-27-8-7-24-16-25(37)9-11-32(24,5)29(27)17-28(26)21(2)18-33/h20,22,24,26-27,29-31H,7-19H2,1-6H3/t20-,22+,24+,26-,27-,29-,30+,31-,32-,33-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	<20	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc.					Assay Description C3H10T1/2 cells were plated in 96 wells with a density of 8×103 cells/well. Cells were grown to confluence (72 hrs). After sonic Hedgehog (250 ng/ml)...				Bioorg Med Chem Lett 18: 1994-9 (2008) BindingDB Entry DOI: 10.7270/Q2QR50GW
					More data for this Ligand-Target Pair