BDBM396280 US10314827, Compound 35

SMILES: C[C@@H]1[C@@H]2NC[C@@H](C)C[C@H]2O[C@]11CC[C@H]2[C@@H]3CC[C@@H]4C[C@H](CC[C@]4(C)[C@H]3CC2=C(C)C1)OC(C)=O

InChI Key: InChIKey=PVBOHVWWWYCIGX-FJBHCLDISA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 396280   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Alkaline phosphatase placental-like (Homo sapiens (Human))	BDBM396280 (US10314827, Compound 35) Show SMILES C[C@@H]1[C@@H]2NC[C@@H](C)C[C@H]2O[C@]11CC[C@H]2[C@@H]3CC[C@@H]4C[C@H](CC[C@]4(C)[C@H]3CC2=C(C)C1)OC(C)=O |r,t:31| Show InChI InChI=1S/C30H47NO3/c1-17-12-27-28(31-16-17)19(3)30(34-27)11-9-23-24-7-6-21-13-22(33-20(4)32)8-10-29(21,5)26(24)14-25(23)18(2)15-30/h17,19,21-24,26-28,31H,6-16H2,1-5H3/t17-,19+,21+,22-,23-,24-,26-,27+,28-,29-,30-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	<20	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc.					Assay Description C3H10T1/2 cells were plated in 96 wells with a density of 8×103 cells/well. Cells were grown to confluence (72 hrs). After sonic Hedgehog (250 ng/ml)...				Bioorg Med Chem Lett 18: 1994-9 (2008) BindingDB Entry DOI: 10.7270/Q2QR50GW
					More data for this Ligand-Target Pair