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SMILES: FC(F)(F)c1cccc(COc2ccc(Br)cc2OC2CNC2)c1

InChI Key: InChIKey=CWAYESQBOZBJAS-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 396383   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium-dependent serotonin transporter (Homo sapiens (Human))	BDBM396383 (3-[5-Bromo-2-(3-trifluoromethyl-benzyloxy)-phenoxy...) Show SMILES FC(F)(F)c1cccc(COc2ccc(Br)cc2OC2CNC2)c1 Show InChI InChI=1S/C17H15BrF3NO2/c18-13-4-5-15(16(7-13)24-14-8-22-9-14)23-10-11-2-1-3-12(6-11)17(19,20)21/h1-7,14,22H,8-10H2	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Novartis					Assay Description Receptor binding was performed using membrane fractions prepared from the HEK-293 cell line recombinantly expressing rat 5-HT7 receptors (NCBI access...				J Med Chem 52: 3523-38 (2009) BindingDB Entry DOI: 10.7270/Q26T0Q0F
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Rattus norvegicus (rat))	BDBM396383 (3-[5-Bromo-2-(3-trifluoromethyl-benzyloxy)-phenoxy...) Show SMILES FC(F)(F)c1cccc(COc2ccc(Br)cc2OC2CNC2)c1 Show InChI InChI=1S/C17H15BrF3NO2/c18-13-4-5-15(16(7-13)24-14-8-22-9-14)23-10-11-2-1-3-12(6-11)17(19,20)21/h1-7,14,22H,8-10H2	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Novartis					Assay Description Receptor binding was performed using membrane fractions prepared from the HEK-293 cell line recombinantly expressing rat 5-HT7 receptors (NCBI access...				J Med Chem 52: 3523-38 (2009) BindingDB Entry DOI: 10.7270/Q26T0Q0F
					More data for this Ligand-Target Pair