null

SMILES: Cc1c(C(=O)C(=O)NC2(COC2)C(F)(F)F)c2CCCn2c1C(=O)Nc1ccc(F)c(Cl)c1

InChI Key: InChIKey=OSDGRCKRFQBWTF-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 400028   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium/bile acid cotransporter (Homo sapiens (Human))	BDBM400028 (N-(3-chloro-4-fluorophenyl)-6-methyl-7-(2-oxo-2-((...) Show SMILES Cc1c(C(=O)C(=O)NC2(COC2)C(F)(F)F)c2CCCn2c1C(=O)Nc1ccc(F)c(Cl)c1 Show InChI InChI=1S/C21H18ClF4N3O4/c1-10-15(17(30)19(32)28-20(8-33-9-20)21(24,25)26)14-3-2-6-29(14)16(10)18(31)27-11-4-5-13(23)12(22)7-11/h4-5,7H,2-3,6,8-9H2,1H3,(H,27,31)(H,28,32)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	5.80	n/a	n/a	n/a	n/a
University of California at Los Angeles					Assay Description A HepG2 cell line overexpressing the HBV virus attachment receptor sodium-taurocholate cotransporting polypeptide (NTCP) was grown to confluency in D...				Bioorg Med Chem 17: 7174-85 (2009) BindingDB Entry DOI: 10.7270/Q28G8P1P
					More data for this Ligand-Target Pair
Sodium/bile acid cotransporter (Homo sapiens (Human))	BDBM400028 (N-(3-chloro-4-fluorophenyl)-6-methyl-7-(2-oxo-2-((...) Show SMILES Cc1c(C(=O)C(=O)NC2(COC2)C(F)(F)F)c2CCCn2c1C(=O)Nc1ccc(F)c(Cl)c1 Show InChI InChI=1S/C21H18ClF4N3O4/c1-10-15(17(30)19(32)28-20(8-33-9-20)21(24,25)26)14-3-2-6-29(14)16(10)18(31)27-11-4-5-13(23)12(22)7-11/h4-5,7H,2-3,6,8-9H2,1H3,(H,27,31)(H,28,32)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	5.80	n/a	n/a	n/a	n/a
Celgene Quantical Research, Inc. US Patent									US Patent US9714230 (2017) BindingDB Entry DOI: 10.7270/Q2BR8X9J
					More data for this Ligand-Target Pair
Capsid protein (Hepatitis B virus genotype C subtype ayr (isolate ...)	BDBM400028 (N-(3-chloro-4-fluorophenyl)-6-methyl-7-(2-oxo-2-((...) Show SMILES Cc1c(C(=O)C(=O)NC2(COC2)C(F)(F)F)c2CCCn2c1C(=O)Nc1ccc(F)c(Cl)c1 Show InChI InChI=1S/C21H18ClF4N3O4/c1-10-15(17(30)19(32)28-20(8-33-9-20)21(24,25)26)14-3-2-6-29(14)16(10)18(31)27-11-4-5-13(23)12(22)7-11/h4-5,7H,2-3,6,8-9H2,1H3,(H,27,31)(H,28,32)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	5.80	n/a	n/a	n/a	n/a
GILEAD SCIENCES, INC. US Patent					Assay Description A HepG2 cell line overexpressing the HBV virus attachment receptor sodium-taurocholate cotransporting polypeptide (NTCP) was grown to confluency in D...				US Patent US10874640 (2020) BindingDB Entry DOI: 10.7270/Q2KD220M
					More data for this Ligand-Target Pair