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SMILES: CN1C(=O)COc2cc(Nc3cc4n(CCC5CC5)cnc4cc3F)cnc12

InChI Key: InChIKey=KZQDVQHLDALCGY-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 400239   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Gamma-aminobutyric acid receptor subunit alpha-5


(Homo sapiens (Human))		BDBM400239
PNG
(7-((1-(2-Cyclopropylethyl)-5-fluoro-1H-benzo[d]imi...)
Show SMILES CN1C(=O)COc2cc(Nc3cc4n(CCC5CC5)cnc4cc3F)cnc12
Show InChI InChI=1S/C20H20FN5O2/c1-25-19(27)10-28-18-6-13(9-22-20(18)25)24-15-8-17-16(7-14(15)21)23-11-26(17)5-4-12-2-3-12/h6-9,11-12,24H,2-5,10H2,1H3
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US Patent
 4.10n/an/an/an/an/an/an/an/a



Ono Pharmaceutical Co., Ltd

US Patent


Assay Description
The GABAAα5/β3/γ2 protein used for the Scintillation Proximity Assay was derived from membranes produced from HEK293 GABAA α5/ ...

US Patent US10016439 (2018)


BindingDB Entry DOI: 10.7270/Q2NC63J0
More data for this
Ligand-Target Pair