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SMILES: O=C(Nc1nc(n[nH]1)C(=O)NC1CC1)c1csc(n1)-c1ccc2OCCc2c1

InChI Key: InChIKey=CIUBDKYTODWZOK-UHFFFAOYSA-N

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   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 401561   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Dual specificity tyrosine-phosphorylation-regulated kinase 1B


(Homo sapiens (Human))		BDBM401561
PNG
(US10005769, No. 25)
Show SMILES O=C(Nc1nc(n[nH]1)C(=O)NC1CC1)c1csc(n1)-c1ccc2OCCc2c1
Show InChI InChI=1S/C18H16N6O3S/c25-15(22-18-21-14(23-24-18)16(26)19-11-2-3-11)12-8-28-17(20-12)10-1-4-13-9(7-10)5-6-27-13/h1,4,7-8,11H,2-3,5-6H2,(H,19,26)(H2,21,22,23,24,25)
UniProtKB/SwissProt

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PC cid
PC sid
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US Patent
n/an/a 3.51n/an/an/an/an/an/a



Pfizer



Assay Description
The substrate DYRKtide (synthetic peptide RRRFRPASPLRGPPK) was dissolved in freshly prepared Base Reaction Buffer (20 mM Hepes (pH 7.5), 10 mM MgCl2,...

Bioorg Med Chem Lett 19: 908-11 (2009)


BindingDB Entry DOI: 10.7270/Q2F19224
More data for this
Ligand-Target Pair