null

SMILES: C[C@@H]1CC[C@H](CN1C(=O)c1ccc(F)cc1-n1nccn1)n1cc(cn1)C(C)(C)O

InChI Key: InChIKey=MJTYFEGLXSYIAG-RHSMWYFYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 401875   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Orexin/Hypocretin receptor type 1 (Homo sapiens (Human))	BDBM401875 (2-{1-[(3R,6R)-1-{[4-Fluoro-2-(2H- 1,2,3-triazol-2-...) Show SMILES C[C@@H]1CC[C@H](CN1C(=O)c1ccc(F)cc1-n1nccn1)n1cc(cn1)C(C)(C)O |r| Show InChI InChI=1S/C21H25FN6O2/c1-14-4-6-17(27-12-15(11-25-27)21(2,3)30)13-26(14)20(29)18-7-5-16(22)10-19(18)28-23-8-9-24-28/h5,7-12,14,17,30H,4,6,13H2,1-3H3/t14-,17-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Manchester					Assay Description For intracellular calcium measurements, Chinese hamster ovary (CHO) cells expressing the rat orexin-1 receptor or the human orexin-2 receptor, are gr...				J Med Chem 52: 7142-56 (2009) BindingDB Entry DOI: 10.7270/Q2S75JPN
					More data for this Ligand-Target Pair
Orexin/Hypocretin receptor type 1 (Rattus norvegicus (Rat))	BDBM401875 (2-{1-[(3R,6R)-1-{[4-Fluoro-2-(2H- 1,2,3-triazol-2-...) Show SMILES C[C@@H]1CC[C@H](CN1C(=O)c1ccc(F)cc1-n1nccn1)n1cc(cn1)C(C)(C)O |r| Show InChI InChI=1S/C21H25FN6O2/c1-14-4-6-17(27-12-15(11-25-27)21(2,3)30)13-26(14)20(29)18-7-5-16(22)10-19(18)28-23-8-9-24-28/h5,7-12,14,17,30H,4,6,13H2,1-3H3/t14-,17-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	18.8	n/a	n/a	n/a	n/a	n/a	n/a
University of Manchester					Assay Description For intracellular calcium measurements, Chinese hamster ovary (CHO) cells expressing the rat orexin-1 receptor or the human orexin-2 receptor, are gr...				J Med Chem 52: 7142-56 (2009) BindingDB Entry DOI: 10.7270/Q2S75JPN
					More data for this Ligand-Target Pair