BDBM4032 2-{[1,6-dimethyl-3-(phenylcarbamoyl)-1H-indol-2-yl]disulfanyl}-1,6-dimethyl-N-phenyl-1H-indole-3-carboxamide::dithiobis(1H-indole-3-carboxamide) deriv. 10q

SMILES: Cc1ccc2c(C(=O)Nc3ccccc3)c(SSc3c(C(=O)Nc4ccccc4)c4ccc(C)cc4n3C)n(C)c2c1

InChI Key: InChIKey=RIWLLXKPZKILLE-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 4032   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase transforming protein Src (Avian sarcoma virus)	BDBM4032 (2-{[1,6-dimethyl-3-(phenylcarbamoyl)-1H-indol-2-yl...) Show SMILES Cc1ccc2c(C(=O)Nc3ccccc3)c(SSc3c(C(=O)Nc4ccccc4)c4ccc(C)cc4n3C)n(C)c2c1 Show InChI InChI=1S/C34H30N4O2S2/c1-21-15-17-25-27(19-21)37(3)33(29(25)31(39)35-23-11-7-5-8-12-23)41-42-34-30(32(40)36-24-13-9-6-10-14-24)26-18-16-22(2)20-28(26)38(34)4/h5-20H,1-4H3,(H,35,39)(H,36,40)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Auckland					Assay Description IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...				J Med Chem 37: 2033-42 (1994) Article DOI: 10.1021/jm00039a016 BindingDB Entry DOI: 10.7270/Q2H41PMC
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM4032 (2-{[1,6-dimethyl-3-(phenylcarbamoyl)-1H-indol-2-yl...) Show SMILES Cc1ccc2c(C(=O)Nc3ccccc3)c(SSc3c(C(=O)Nc4ccccc4)c4ccc(C)cc4n3C)n(C)c2c1 Show InChI InChI=1S/C34H30N4O2S2/c1-21-15-17-25-27(19-21)37(3)33(29(25)31(39)35-23-11-7-5-8-12-23)41-42-34-30(32(40)36-24-13-9-6-10-14-24)26-18-16-22(2)20-28(26)38(34)4/h5-20H,1-4H3,(H,35,39)(H,36,40)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Auckland					Assay Description IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...				J Med Chem 37: 2033-42 (1994) Article DOI: 10.1021/jm00039a016 BindingDB Entry DOI: 10.7270/Q2H41PMC
					More data for this Ligand-Target Pair