BDBM404211 (2S,5R)-5-(2-cyanophenyl)-1-(2'-methoxy-[1,1'-biphenyl]-4-carbonyl)pyrrolidine-2-carboxylic acid::US10017468, Compound 386::US10781171, Compound 376

SMILES: OC(=O)[C@@H]1CC[C@@H](N1C(=O)C1CCN(CC1)c1ccc(cc1[N+]([O-])=O)C(F)(F)F)c1ccccc1Cl

InChI Key: InChIKey=AGQCXWGBBORZCD-QUCCMNQESA-N

Data: 1 KI  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 404211   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Free fatty acid receptor 2 (Homo sapiens (Human))	BDBM404211 ((2S,5R)-5-(2-cyanophenyl)-1-(2'-methoxy-[1,1'-biph...) Show SMILES OC(=O)[C@@H]1CC[C@@H](N1C(=O)C1CCN(CC1)c1ccc(cc1[N+]([O-])=O)C(F)(F)F)c1ccccc1Cl Show InChI InChI=1S/C24H23ClF3N3O5/c25-17-4-2-1-3-16(17)18-7-8-20(23(33)34)30(18)22(32)14-9-11-29(12-10-14)19-6-5-15(24(26,27)28)13-21(19)31(35)36/h1-6,13-14,18,20H,7-12H2,(H,33,34)/t18-,20+/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Epics Therapeutics US Patent					Assay Description Human GPR43 radioligand binding assay is performed by adding successively in the wells of a 96 well plate (Master Block, Greiner, 786201), 50 ul of c...				US Patent US10781171 (2020)
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Homo sapiens (Human))	BDBM404211 ((2S,5R)-5-(2-cyanophenyl)-1-(2'-methoxy-[1,1'-biph...) Show SMILES OC(=O)[C@@H]1CC[C@@H](N1C(=O)C1CCN(CC1)c1ccc(cc1[N+]([O-])=O)C(F)(F)F)c1ccccc1Cl Show InChI InChI=1S/C24H23ClF3N3O5/c25-17-4-2-1-3-16(17)18-7-8-20(23(33)34)30(18)22(32)14-9-11-29(12-10-14)19-6-5-15(24(26,27)28)13-21(19)31(35)36/h1-6,13-14,18,20H,7-12H2,(H,33,34)/t18-,20+/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	600	n/a	n/a	n/a	n/a
Ogeda SA US Patent					Assay Description The following assay can be used for determination of GPR43 activation. When a GPCR is in its active state, either as a result of ligand binding or co...				US Patent US10017468 (2018) BindingDB Entry DOI: 10.7270/Q2HM5BST
					More data for this Ligand-Target Pair