BDBM4084 5-benzyl-2,3,7,8-tetrahydroxy-5,6-dihydrophenanthridin-6-one::Phenanthridinone deriv. 5f

SMILES: Oc1cc2n(Cc3ccccc3)c(=O)c3c(O)c(O)ccc3c2cc1O

InChI Key: InChIKey=XNUDZGSOZAWWNT-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 4084   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP-Dependent Protein Kinase (PKA) (Bos taurus (bovine))	BDBM4084 (5-benzyl-2,3,7,8-tetrahydroxy-5,6-dihydrophenanthr...) Show SMILES Oc1cc2n(Cc3ccccc3)c(=O)c3c(O)c(O)ccc3c2cc1O Show InChI InChI=1S/C20H15NO5/c22-15-7-6-12-13-8-16(23)17(24)9-14(13)21(20(26)18(12)19(15)25)10-11-4-2-1-3-5-11/h1-9,22-25H,10H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.84E+5	n/a	n/a	n/a	n/a	7.4	30
Pfizer					Assay Description IC50 is the inhibitor concentration, which inhibits 50% of PKA activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] label...				J Med Chem 37: 2224-31 (1994) Article DOI: 10.1021/jm00040a015 BindingDB Entry DOI: 10.7270/Q27M0648
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM4084 (5-benzyl-2,3,7,8-tetrahydroxy-5,6-dihydrophenanthr...) Show SMILES Oc1cc2n(Cc3ccccc3)c(=O)c3c(O)c(O)ccc3c2cc1O Show InChI InChI=1S/C20H15NO5/c22-15-7-6-12-13-8-16(23)17(24)9-14(13)21(20(26)18(12)19(15)25)10-11-4-2-1-3-5-11/h1-9,22-25H,10H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.10E+4	n/a	n/a	n/a	n/a	7.4	30
Pfizer					Assay Description IC50 is the inhibitor concentration, which inhibits 50% of pp60c-src activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] ...				J Med Chem 37: 2224-31 (1994) Article DOI: 10.1021/jm00040a015 BindingDB Entry DOI: 10.7270/Q27M0648
					More data for this Ligand-Target Pair