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SMILES: CC#CCn1c(nc2n(C)c(=O)n(Cc3cccc(F)c3C#N)c(=O)c12)N1CCC[C@@H](N)C1

InChI Key: InChIKey=KUZKTFDTPDKZQW-MRXNPFEDSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 408607   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Dipeptidyl peptidase 4


(Homo sapiens (Human))		BDBM408607
PNG
(US10358449, Compound I-1)
Show SMILES CC#CCn1c(nc2n(C)c(=O)n(Cc3cccc(F)c3C#N)c(=O)c12)N1CCC[C@@H](N)C1 |r|
Show InChI InChI=1S/C23H24FN7O2/c1-3-4-11-30-19-20(27-22(30)29-10-6-8-16(26)14-29)28(2)23(33)31(21(19)32)13-15-7-5-9-18(24)17(15)12-25/h5,7,9,16H,6,8,10-11,13-14,26H2,1-2H3/t16-/m1/s1
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PC cid
PC sid
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US Patent
n/an/a 0.210n/an/an/an/an/an/a



Jiangsu Tasly Diyi Pharmaceutical Co, LTD.

US Patent


Assay Description
DPP-IV could hydrolyze Gly-Pro-Aminoluciferin at room temperature to generate Aminoluciferin, which could produce “glow type” luminescent signals in ...

US Patent US10358449 (2019)


BindingDB Entry DOI: 10.7270/Q29S1TCK
More data for this
Ligand-Target Pair