BDBM4088 5-[(3,4-dichlorophenyl)methyl]-2,3,7,8-tetrahydroxy-5,6-dihydrophenanthridin-6-one::Phenanthridinone deriv. 5j

SMILES: Oc1ccc2c3cc(O)c(O)cc3n(Cc3ccc(Cl)c(Cl)c3)c(=O)c2c1O

InChI Key: InChIKey=XRZJWPUIFWIDRE-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 4088   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP-Dependent Protein Kinase (PKA) (Bos taurus (bovine))	BDBM4088 (5-[(3,4-dichlorophenyl)methyl]-2,3,7,8-tetrahydrox...) Show SMILES Oc1ccc2c3cc(O)c(O)cc3n(Cc3ccc(Cl)c(Cl)c3)c(=O)c2c1O Show InChI InChI=1S/C20H13Cl2NO5/c21-12-3-1-9(5-13(12)22)8-23-14-7-17(26)16(25)6-11(14)10-2-4-15(24)19(27)18(10)20(23)28/h1-7,24-27H,8H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.10E+5	n/a	n/a	n/a	n/a	7.4	30
Pfizer					Assay Description IC50 is the inhibitor concentration, which inhibits 50% of PKA activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] label...				J Med Chem 37: 2224-31 (1994) Article DOI: 10.1021/jm00040a015 BindingDB Entry DOI: 10.7270/Q27M0648
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM4088 (5-[(3,4-dichlorophenyl)methyl]-2,3,7,8-tetrahydrox...) Show SMILES Oc1ccc2c3cc(O)c(O)cc3n(Cc3ccc(Cl)c(Cl)c3)c(=O)c2c1O Show InChI InChI=1S/C20H13Cl2NO5/c21-12-3-1-9(5-13(12)22)8-23-14-7-17(26)16(25)6-11(14)10-2-4-15(24)19(27)18(10)20(23)28/h1-7,24-27H,8H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.97E+5	n/a	n/a	n/a	n/a	7.4	30
Pfizer					Assay Description IC50 is the inhibitor concentration, which inhibits 50% of pp60c-src activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] ...				J Med Chem 37: 2224-31 (1994) Article DOI: 10.1021/jm00040a015 BindingDB Entry DOI: 10.7270/Q27M0648
					More data for this Ligand-Target Pair