BDBM409012 US10377744, Compound No. 32

SMILES: Fc1cc(NC(=O)NC2CCN(CC2)C(=O)C2CC2)ccc1C(F)(F)F

InChI Key: InChIKey=IIGBRXYVEOEPDV-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 409012   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
EBifunctional epoxide hydrolase 2 (Homo sapiens (Human))	BDBM409012 (US10377744, Compound No. 32 | US11123311, Compound...) Show SMILES Fc1cc(NC(=O)NC2CCN(CC2)C(=O)C2CC2)ccc1C(F)(F)F Show InChI InChI=1S/C17H19F4N3O2/c18-14-9-12(3-4-13(14)17(19,20)21)23-16(26)22-11-5-7-24(8-6-11)15(25)10-1-2-10/h3-4,9-11H,1-2,5-8H2,(H2,22,23,26)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.380	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Eicosis, LLC US Patent					Assay Description FRET assays to determine Ki for the compounds of Table I were carried out as described previously (Lee et al. Analytical Biochemistry 434 (2013) 259-...				US Patent US10377744 (2019) BindingDB Entry DOI: 10.7270/Q2N3009K
					More data for this Ligand-Target Pair
EBifunctional epoxide hydrolase 2 (Homo sapiens (Human))	BDBM409012 (US10377744, Compound No. 32 | US11123311, Compound...) Show SMILES Fc1cc(NC(=O)NC2CCN(CC2)C(=O)C2CC2)ccc1C(F)(F)F Show InChI InChI=1S/C17H19F4N3O2/c18-14-9-12(3-4-13(14)17(19,20)21)23-16(26)22-11-5-7-24(8-6-11)15(25)10-1-2-10/h3-4,9-11H,1-2,5-8H2,(H2,22,23,26)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		0.380	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
EBifunctional epoxide hydrolase 2 (Homo sapiens (Human))	BDBM409012 (US10377744, Compound No. 32 | US11123311, Compound...) Show SMILES Fc1cc(NC(=O)NC2CCN(CC2)C(=O)C2CC2)ccc1C(F)(F)F Show InChI InChI=1S/C17H19F4N3O2/c18-14-9-12(3-4-13(14)17(19,20)21)23-16(26)22-11-5-7-24(8-6-11)15(25)10-1-2-10/h3-4,9-11H,1-2,5-8H2,(H2,22,23,26)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		0.380	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair