null
SMILES: COc1ccc(OC(F)(F)F)cc1S(=O)(=O)Nc1cncc(c1)-c1cccs1
InChI Key: InChIKey=OTGOENYEEKKTAF-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Alkaline phosphatase, tissue-nonspecific isozyme (Homo sapiens (Human)) | BDBM409907 (US10370333, Example XI-16) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
SANFORD-BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE US Patent | Assay Description To determine the inhibition selectivity for inhibitor candidates, human TNAP, PLAP or IAP were added to microtiter plates followed by addition of the... | US Patent US10370333 (2019) BindingDB Entry DOI: 10.7270/Q2445PVM | |||||||||||
More data for this Ligand-Target Pair |