BDBM41016 2-(3,4-dimethoxyphenyl)-4,5-bis(2-thienyl)-1H-imidazole::2-(3,4-dimethoxyphenyl)-4,5-di-2-thienyl-1H-imidazole::2-(3,4-dimethoxyphenyl)-4,5-dithiophen-2-yl-1H-imidazole::MLS000534650::SMR000142167::cid_1327166
SMILES: COc1ccc(cc1OC)-c1nc(-c2cccs2)c([nH]1)-c1cccs1
InChI Key: InChIKey=HFGNIDNKDQDTGT-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Focal adhesion kinase 1 (Homo sapiens (Human)) | BDBM41016 (2-(3,4-dimethoxyphenyl)-4,5-bis(2-thienyl)-1H-imid...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | PCBioAssay | n/a | n/a | >7.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay | Assay Description Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assa... | PubChem Bioassay (2007) BindingDB Entry DOI: 10.7270/Q2GX48ZN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
streptokinase A precursor (Streptococcus pyogenes M1 GAS) | BDBM41016 (2-(3,4-dimethoxyphenyl)-4,5-bis(2-thienyl)-1H-imid...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | PCBioAssay | n/a | n/a | n/a | n/a | 1.41E+3 | n/a | n/a | n/a | n/a |
Broad Institute Curated by PubChem BioAssay | Assay Description Keywords: Group A streptococcus, GAS, streptokinase, expression, virulence, inhibition, dose response, EC50 Assay Overview: The goal of this assa... | PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2736PBV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
streptokinase A precursor (Streptococcus pyogenes M1 GAS) | BDBM41016 (2-(3,4-dimethoxyphenyl)-4,5-bis(2-thienyl)-1H-imid...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | PCBioAssay | n/a | n/a | n/a | n/a | 5.93E+3 | n/a | n/a | n/a | n/a |
Broad Institute Curated by PubChem BioAssay | Assay Description Keywords: Group A streptococcus, GAS, streptokinase, expression, virulence, inhibition, dose response, EC50 Assay Overview: The goal of this assa... | PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q23F4N1V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
PTK2B protein tyrosine kinase 2 beta (PTK2B) (Homo sapiens (Human)) | BDBM41016 (2-(3,4-dimethoxyphenyl)-4,5-bis(2-thienyl)-1H-imid...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | PCBioAssay | n/a | n/a | >6.95E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay | Assay Description Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa... | PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2H993M3 | |||||||||||
More data for this Ligand-Target Pair |