null

SMILES: Oc1cc2n(C(=O)c3ccc(cc3)C(F)(F)F)c3c(O)c(O)ccc3c2cc1O

InChI Key: InChIKey=BSVHHTYZJHWTDE-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 4111   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP-dependent protein kinase catalytic subunit alpha (Bos taurus (bovine))	BDBM4111 (9-{[4-(trifluoromethyl)phenyl]carbonyl}-9H-carbazo...) Show SMILES Oc1cc2n(C(=O)c3ccc(cc3)C(F)(F)F)c3c(O)c(O)ccc3c2cc1O Show InChI InChI=1S/C20H12F3NO5/c21-20(22,23)10-3-1-9(2-4-10)19(29)24-13-8-16(27)15(26)7-12(13)11-5-6-14(25)18(28)17(11)24/h1-8,25-28H	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer					Assay Description IC50 is the inhibitor concentration, which inhibits 50% of PKA activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] label...				J Med Chem 37: 2224-31 (1994) Article DOI: 10.1021/jm00040a015 BindingDB Entry DOI: 10.7270/Q27M0648
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM4111 (9-{[4-(trifluoromethyl)phenyl]carbonyl}-9H-carbazo...) Show SMILES Oc1cc2n(C(=O)c3ccc(cc3)C(F)(F)F)c3c(O)c(O)ccc3c2cc1O Show InChI InChI=1S/C20H12F3NO5/c21-20(22,23)10-3-1-9(2-4-10)19(29)24-13-8-16(27)15(26)7-12(13)11-5-6-14(25)18(28)17(11)24/h1-8,25-28H	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	700	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer					Assay Description IC50 is the inhibitor concentration, which inhibits 50% of pp60c-src activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] ...				J Med Chem 37: 2224-31 (1994) Article DOI: 10.1021/jm00040a015 BindingDB Entry DOI: 10.7270/Q27M0648
					More data for this Ligand-Target Pair