BDBM4122 9-[(4-nitrobenzene)sulfonyl]-9H-carbazole-1,2,6,7-tetrol::Carbazole deriv. 9ff

SMILES: Oc1ccc2c(c1O)n(c1cc(O)c(O)cc21)S(=O)(=O)c1ccc(cc1)[N+]([O-])=O

InChI Key: InChIKey=NGAARPFEICIRSR-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 4122   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP-dependent protein kinase catalytic subunit alpha (Bos taurus (bovine))	BDBM4122 (9-[(4-nitrobenzene)sulfonyl]-9H-carbazole-1,2,6,7-...) Show SMILES Oc1ccc2c(c1O)n(c1cc(O)c(O)cc21)S(=O)(=O)c1ccc(cc1)[N+]([O-])=O Show InChI InChI=1S/C18H12N2O8S/c21-14-6-5-11-12-7-15(22)16(23)8-13(12)19(17(11)18(14)24)29(27,28)10-3-1-9(2-4-10)20(25)26/h1-8,21-24H	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.68E+5	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer					Assay Description IC50 is the inhibitor concentration, which inhibits 50% of PKA activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] label...				J Med Chem 37: 2224-31 (1994) Article DOI: 10.1021/jm00040a015 BindingDB Entry DOI: 10.7270/Q27M0648
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM4122 (9-[(4-nitrobenzene)sulfonyl]-9H-carbazole-1,2,6,7-...) Show SMILES Oc1ccc2c(c1O)n(c1cc(O)c(O)cc21)S(=O)(=O)c1ccc(cc1)[N+]([O-])=O Show InChI InChI=1S/C18H12N2O8S/c21-14-6-5-11-12-7-15(22)16(23)8-13(12)19(17(11)18(14)24)29(27,28)10-3-1-9(2-4-10)20(25)26/h1-8,21-24H	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer					Assay Description IC50 is the inhibitor concentration, which inhibits 50% of pp60c-src activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] ...				J Med Chem 37: 2224-31 (1994) Article DOI: 10.1021/jm00040a015 BindingDB Entry DOI: 10.7270/Q27M0648
					More data for this Ligand-Target Pair