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SMILES: Oc1ccc2[C@H]([C@H](CCc2c1)c1ccccc1)c1ccc(OCCN2CC(CF)C2)nc1

InChI Key: InChIKey=LWVJGDVSYXHPER-SQHAQQRYSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 412248   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Estrogen receptor


(Homo sapiens (Human))		BDBM412248
PNG
((5S,6S)-5-(6-(2-(3- (fluoromethyl)azetidin- 1-yl)e...)
Show SMILES Oc1ccc2[C@H]([C@H](CCc2c1)c1ccccc1)c1ccc(OCCN2CC(CF)C2)nc1 |r|
Show InChI InChI=1S/C27H29FN2O2/c28-15-19-17-30(18-19)12-13-32-26-11-7-22(16-29-26)27-24(20-4-2-1-3-5-20)9-6-21-14-23(31)8-10-25(21)27/h1-5,7-8,10-11,14,16,19,24,27,31H,6,9,12-13,15,17-18H2/t24-,27+/m1/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
UniChem
US Patent
n/an/an/an/a 0.0460n/an/an/an/a



Genentech, Inc.

US Patent


Assay Description
The relative efficacies of Formula I compounds as inhibitors of an enzyme activity (or other biological activity) can be established by determining t...

US Patent US10399939 (2019)


BindingDB Entry DOI: 10.7270/Q2G73H4H
More data for this
Ligand-Target Pair