BDBM412287 US10399945, Example 26::US10669239, Compound 26::US10927079, Compound 26

SMILES: Cc1cnc(C2CCOCC2)c(NC(=O)N[C@H]2[C@H](O)CC(C)(C)c3ccccc23)c1

InChI Key: InChIKey=DCZVZWOAEFCOIJ-IFMALSPDSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 412287   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM412287 (US10399945, Example 26 | US10669239, Compound 26 |...) Show SMILES Cc1cnc(C2CCOCC2)c(NC(=O)N[C@H]2[C@H](O)CC(C)(C)c3ccccc23)c1 |r| Show InChI InChI=1S/C24H31N3O3/c1-15-12-19(21(25-14-15)16-8-10-30-11-9-16)26-23(29)27-22-17-6-4-5-7-18(17)24(2,3)13-20(22)28/h4-7,12,14,16,20,22,28H,8-11,13H2,1-3H3,(H2,26,27,29)/t20-,22-/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
MOCHIDA PHARMACEUTICAL CO., LTD. US Patent					Assay Description Measurement was carried out using TrkA LanthaScreen (registered trademark) Eu Kinase Binding Assay (ThermoFisher SCIENTIFIC). To a 384 well plate (Co...				US Patent US10399945 (2019) BindingDB Entry DOI: 10.7270/Q2BG2RCB
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM412287 (US10399945, Example 26 | US10669239, Compound 26 |...) Show SMILES Cc1cnc(C2CCOCC2)c(NC(=O)N[C@H]2[C@H](O)CC(C)(C)c3ccccc23)c1 |r| Show InChI InChI=1S/C24H31N3O3/c1-15-12-19(21(25-14-15)16-8-10-30-11-9-16)26-23(29)27-22-17-6-4-5-7-18(17)24(2,3)13-20(22)28/h4-7,12,14,16,20,22,28H,8-11,13H2,1-3H3,(H2,26,27,29)/t20-,22-/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	UniChem	US Patent	n/a	n/a	<0.100	n/a	n/a	n/a	n/a	n/a	n/a
MOCHIDA PHARMACEUTICAL CO., LTD. US Patent					Assay Description Measurement was carried out using TrkA LanthaScreen (registered trademark) Eu Kinase Binding Assay (ThermoFisher SCIENTIFIC). To a 384 well plate (Co...				US Patent US10927079 (2021)
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM412287 (US10399945, Example 26 | US10669239, Compound 26 |...) Show SMILES Cc1cnc(C2CCOCC2)c(NC(=O)N[C@H]2[C@H](O)CC(C)(C)c3ccccc23)c1 |r| Show InChI InChI=1S/C24H31N3O3/c1-15-12-19(21(25-14-15)16-8-10-30-11-9-16)26-23(29)27-22-17-6-4-5-7-18(17)24(2,3)13-20(22)28/h4-7,12,14,16,20,22,28H,8-11,13H2,1-3H3,(H2,26,27,29)/t20-,22-/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
MOCHIDA PHARMACEUTICAL CO., LTD. US Patent					Assay Description Measurement was carried out using TrkA LanthaScreen (registered trademark) Eu Kinase Binding Assay (ThermoFisher SCIENTIFIC). To a 384 well plate (Co...				US Patent US10669239 (2020)
					More data for this Ligand-Target Pair