null

SMILES: Cc1cc(NC(=O)N[C@H]2[C@H](O)CC(C)(C)c3cc(F)c(F)cc23)c(nc1-c1cnn(C)c1)-c1ccccc1

InChI Key: InChIKey=GPOSGKQJPKYGOF-SHQCIBLASA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 412322   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM412322 (US10399945, Example 51 | US10669239, Compound 51 |...) Show SMILES Cc1cc(NC(=O)N[C@H]2[C@H](O)CC(C)(C)c3cc(F)c(F)cc23)c(nc1-c1cnn(C)c1)-c1ccccc1 |r| Show InChI InChI=1S/C29H29F2N5O2/c1-16-10-23(26(17-8-6-5-7-9-17)34-25(16)18-14-32-36(4)15-18)33-28(38)35-27-19-11-21(30)22(31)12-20(19)29(2,3)13-24(27)37/h5-12,14-15,24,27,37H,13H2,1-4H3,(H2,33,35,38)/t24-,27-/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
MOCHIDA PHARMACEUTICAL CO., LTD. US Patent					Assay Description Measurement was carried out using TrkA LanthaScreen (registered trademark) Eu Kinase Binding Assay (ThermoFisher SCIENTIFIC). To a 384 well plate (Co...				US Patent US10399945 (2019) BindingDB Entry DOI: 10.7270/Q2BG2RCB
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM412322 (US10399945, Example 51 | US10669239, Compound 51 |...) Show SMILES Cc1cc(NC(=O)N[C@H]2[C@H](O)CC(C)(C)c3cc(F)c(F)cc23)c(nc1-c1cnn(C)c1)-c1ccccc1 |r| Show InChI InChI=1S/C29H29F2N5O2/c1-16-10-23(26(17-8-6-5-7-9-17)34-25(16)18-14-32-36(4)15-18)33-28(38)35-27-19-11-21(30)22(31)12-20(19)29(2,3)13-24(27)37/h5-12,14-15,24,27,37H,13H2,1-4H3,(H2,33,35,38)/t24-,27-/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	UniChem	US Patent	n/a	n/a	<0.100	n/a	n/a	n/a	n/a	n/a	n/a
MOCHIDA PHARMACEUTICAL CO., LTD. US Patent					Assay Description Measurement was carried out using TrkA LanthaScreen (registered trademark) Eu Kinase Binding Assay (ThermoFisher SCIENTIFIC). To a 384 well plate (Co...				US Patent US10927079 (2021)
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM412322 (US10399945, Example 51 | US10669239, Compound 51 |...) Show SMILES Cc1cc(NC(=O)N[C@H]2[C@H](O)CC(C)(C)c3cc(F)c(F)cc23)c(nc1-c1cnn(C)c1)-c1ccccc1 |r| Show InChI InChI=1S/C29H29F2N5O2/c1-16-10-23(26(17-8-6-5-7-9-17)34-25(16)18-14-32-36(4)15-18)33-28(38)35-27-19-11-21(30)22(31)12-20(19)29(2,3)13-24(27)37/h5-12,14-15,24,27,37H,13H2,1-4H3,(H2,33,35,38)/t24-,27-/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
MOCHIDA PHARMACEUTICAL CO., LTD. US Patent					Assay Description Measurement was carried out using TrkA LanthaScreen (registered trademark) Eu Kinase Binding Assay (ThermoFisher SCIENTIFIC). To a 384 well plate (Co...				US Patent US10669239 (2020)
					More data for this Ligand-Target Pair