BDBM412513 (Z)-N-(5-(1-(4-bromophenyl)prop-1- en-1-yl)pyrazin-2-yl)-5-fluoro-4- methylnicotinamide::US10399967, Compound 146

SMILES: C\C=C(\c1ccc(Br)cc1)c1cnc(NC(=O)c2cncc(F)c2C)cn1

InChI Key: InChIKey=LPNGUNKXNPYWTD-CQPUUCJISA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 412513   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Interleukin-2 (Homo sapiens (Human))	BDBM412513 ((Z)-N-(5-(1-(4-bromophenyl)prop-1- en-1-yl)pyrazin...) Show SMILES C\C=C(\c1ccc(Br)cc1)c1cnc(NC(=O)c2cncc(F)c2C)cn1 Show InChI InChI=1S/C20H16BrFN4O/c1-3-15(13-4-6-14(21)7-5-13)18-10-25-19(11-24-18)26-20(27)16-8-23-9-17(22)12(16)2/h3-11H,1-2H3,(H,25,26,27)/b15-3-	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	UniChem	US Patent	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
PRCL RESEARCH INC. US Patent					Assay Description Human peripheral blood mononuclear cells (PBMCs) are prepared from heparinized human blood by separation over a Ficoll density gradient.PBMCs are sti...				US Patent US10399967 (2019) BindingDB Entry DOI: 10.7270/Q2Z89FRQ
					More data for this Ligand-Target Pair