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SMILES: C[C@@H]1Cc2ncnc([C@@H]3C[C@@H]4CC[C@H](C3)N4S(C)(=O)=O)c2CN1c1cc(Cl)nc2[nH]ccc12

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 414022   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
ATR-interacting protein/Serine/threonine-protein kinase ATR (Homo sapiens (Human))	BDBM414022 (US10421765, Example 11b) Show SMILES C[C@@H]1Cc2ncnc([C@@H]3C[C@@H]4CC[C@H](C3)N4S(C)(=O)=O)c2CN1c1cc(Cl)nc2[nH]ccc12 |r,THB:16:15:8.9.14:11.12| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	329	n/a	n/a	n/a	n/a	n/a	n/a
Board of Regents, The University of Texas System US Patent					Assay Description Human full-length FLAG-TEV-ATR and His6-ATRIP were co-expressed in HEK293 cells. The cell pellet (20 g) was harvested and lysed in 100 mL of lysis bu...				US Patent US10421765 (2019) BindingDB Entry DOI: 10.7270/Q2F47RHH
					More data for this Ligand-Target Pair