null
SMILES: CC1Cc2ncnc(-c3cccc(c3)S(C)(=O)=O)c2CN1c1ccnc2[nH]ccc12
InChI Key:
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
ATR-interacting protein/Serine/threonine-protein kinase ATR (Homo sapiens (Human)) | BDBM414026 (4-(3-methanesulfonyl- phenyl)-7-methyl-6-{1H- pyrr...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 5.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Board of Regents, The University of Texas System; ChemPartner Corporation US Patent | Assay Description Human full-length FLAG-TEV-ATR and His6-ATRIP were co-expressed in HEK293 cells. The cell pellet (20 g) was harvested and lysed in 100 mL of lysis bu... | US Patent US10745420 (2020) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ATR-interacting protein/Serine/threonine-protein kinase ATR (Homo sapiens (Human)) | BDBM414026 (4-(3-methanesulfonyl- phenyl)-7-methyl-6-{1H- pyrr...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 5.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Board of Regents, The University of Texas System US Patent | Assay Description Human full-length FLAG-TEV-ATR and His6-ATRIP were co-expressed in HEK293 cells. The cell pellet (20 g) was harvested and lysed in 100 mL of lysis bu... | US Patent US10421765 (2019) BindingDB Entry DOI: 10.7270/Q2F47RHH | |||||||||||
More data for this Ligand-Target Pair |