BDBM41812 (1,1-Dioxo-1H-1lambda*6*-benzo[d]isothiazol-3-yl)-(4-methoxy-phenyl)-methyl-amine::(1,1-diketo-1,2-benzothiazol-3-yl)-(4-methoxyphenyl)-methyl-amine::MLS000068583::N-(4-methoxyphenyl)-N-methyl-1,1-bis(oxidanylidene)-1,2-benzothiazol-3-amine::N-(4-methoxyphenyl)-N-methyl-1,1-dioxo-1,2-benzothiazol-3-amine::SMR000122953::cid_785727

SMILES: COc1ccc(cc1)N(C)C1=NS(=O)(=O)c2ccccc12

InChI Key: InChIKey=LLZMQRONMABMKW-UHFFFAOYSA-N

Data: 1 IC50  2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 41812   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase PLK1 (Homo sapiens (Human))	BDBM41812 ((1,1-Dioxo-1H-1lambda*6*-benzo[d]isothiazol-3-yl)-...) Show SMILES COc1ccc(cc1)N(C)C1=NS(=O)(=O)c2ccccc12 |t:11| Show InChI InChI=1S/C15H14N2O3S/c1-17(11-7-9-12(20-2)10-8-11)15-13-5-3-4-6-14(13)21(18,19)16-15/h3-10H,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a
University of Pittsburgh Molecular Library Screening Center Curated by PubChem BioAssay					Assay Description List of compounds to be tested: Compounds that met the active criterion of Z-score is				PubChem Bioassay (2007) BindingDB Entry DOI: 10.7270/Q2Z036KJ
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase PLK1 (Homo sapiens (Human))	BDBM41812 ((1,1-Dioxo-1H-1lambda*6*-benzo[d]isothiazol-3-yl)-...) Show SMILES COc1ccc(cc1)N(C)C1=NS(=O)(=O)c2ccccc12 |t:11| Show InChI InChI=1S/C15H14N2O3S/c1-17(11-7-9-12(20-2)10-8-11)15-13-5-3-4-6-14(13)21(18,19)16-15/h3-10H,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a
University of Pittsburgh Molecular Library Screening Center Curated by PubChem BioAssay					Assay Description List of compounds to be tested: Compounds that met the active criterion of Z-score is				PubChem Bioassay (2007) BindingDB Entry DOI: 10.7270/Q2N58JS6
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase PLK1 (Homo sapiens (Human))	BDBM41812 ((1,1-Dioxo-1H-1lambda*6*-benzo[d]isothiazol-3-yl)-...) Show SMILES COc1ccc(cc1)N(C)C1=NS(=O)(=O)c2ccccc12 |t:11| Show InChI InChI=1S/C15H14N2O3S/c1-17(11-7-9-12(20-2)10-8-11)15-13-5-3-4-6-14(13)21(18,19)16-15/h3-10H,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Pittsburgh Molecular Library Screening Center Curated by PubChem BioAssay					Assay Description List of compounds to be tested: Compounds that met the active criterion of Z-score is				PubChem Bioassay (2007) BindingDB Entry DOI: 10.7270/Q2T72FVT
					More data for this Ligand-Target Pair