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SMILES: Cc1cccc(C)c1NC1=NC(=S)N(c2ccccc2)C11CCOC(C)(C)C1

InChI Key: InChIKey=XOQWQVNJXRZWGS-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 41820   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase PLK1 (Homo sapiens (Human))	BDBM41820 (4-(2,6-dimethylanilino)-7,7-dimethyl-1-phenyl-8-ox...) Show SMILES Cc1cccc(C)c1NC1=NC(=S)N(c2ccccc2)C11CCOC(C)(C)C1 |t:10| Show InChI InChI=1S/C23H27N3OS/c1-16-9-8-10-17(2)19(16)24-20-23(13-14-27-22(3,4)15-23)26(21(28)25-20)18-11-6-5-7-12-18/h5-12H,13-15H2,1-4H3,(H,24,25,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	PCBioAssay	n/a	n/a	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a
University of Pittsburgh Molecular Library Screening Center Curated by PubChem BioAssay					Assay Description List of compounds to be tested: Compounds that met the active criterion of Z-score is				PubChem Bioassay (2007) BindingDB Entry DOI: 10.7270/Q2Z036KJ
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase PLK1 (Homo sapiens (Human))	BDBM41820 (4-(2,6-dimethylanilino)-7,7-dimethyl-1-phenyl-8-ox...) Show SMILES Cc1cccc(C)c1NC1=NC(=S)N(c2ccccc2)C11CCOC(C)(C)C1 |t:10| Show InChI InChI=1S/C23H27N3OS/c1-16-9-8-10-17(2)19(16)24-20-23(13-14-27-22(3,4)15-23)26(21(28)25-20)18-11-6-5-7-12-18/h5-12H,13-15H2,1-4H3,(H,24,25,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	PCBioAssay	n/a	n/a	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a
University of Pittsburgh Molecular Library Screening Center Curated by PubChem BioAssay					Assay Description List of compounds to be tested: Compounds that met the active criterion of Z-score is				PubChem Bioassay (2007) BindingDB Entry DOI: 10.7270/Q2N58JS6
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase PLK1 (Homo sapiens (Human))	BDBM41820 (4-(2,6-dimethylanilino)-7,7-dimethyl-1-phenyl-8-ox...) Show SMILES Cc1cccc(C)c1NC1=NC(=S)N(c2ccccc2)C11CCOC(C)(C)C1 |t:10| Show InChI InChI=1S/C23H27N3OS/c1-16-9-8-10-17(2)19(16)24-20-23(13-14-27-22(3,4)15-23)26(21(28)25-20)18-11-6-5-7-12-18/h5-12H,13-15H2,1-4H3,(H,24,25,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	PCBioAssay	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Pittsburgh Molecular Library Screening Center Curated by PubChem BioAssay					Assay Description List of compounds to be tested: Compounds that met the active criterion of Z-score is				PubChem Bioassay (2007) BindingDB Entry DOI: 10.7270/Q2T72FVT
					More data for this Ligand-Target Pair