null

SMILES: Fc1cc(ccc1C(=O)NC1CC1)N1CCN(Cc2ccc3c4NCCCc4c(=O)[nH]c3c2)CC1

InChI Key: InChIKey=UOAHTPZUUUBPBK-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 419740   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human))	BDBM419740 (US10464919, Example 78) Show SMILES Fc1cc(ccc1C(=O)NC1CC1)N1CCN(Cc2ccc3c4NCCCc4c(=O)[nH]c3c2)CC1 Show InChI InChI=1S/C27H30FN5O2/c28-23-15-19(6-8-20(23)26(34)30-18-4-5-18)33-12-10-32(11-13-33)16-17-3-7-21-24(14-17)31-27(35)22-2-1-9-29-25(21)22/h3,6-8,14-15,18,29H,1-2,4-5,9-13,16H2,(H,30,34)(H,31,35)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	6.64	n/a	n/a	n/a	n/a	n/a	n/a
Je Il Pharmaceutical Co., Ltd. US Patent					Assay Description The PARP-1 enzyme inhibitory activities of the compounds of the present invention were assayed in the following manner by use of a kit (cat. 80551) p...				US Patent US10464919 (2019) BindingDB Entry DOI: 10.7270/Q2736T8M
					More data for this Ligand-Target Pair
Activated CDC42 kinase 1 (Homo sapiens (Human))	BDBM419740 (US10464919, Example 78) Show SMILES Fc1cc(ccc1C(=O)NC1CC1)N1CCN(Cc2ccc3c4NCCCc4c(=O)[nH]c3c2)CC1 Show InChI InChI=1S/C27H30FN5O2/c28-23-15-19(6-8-20(23)26(34)30-18-4-5-18)33-12-10-32(11-13-33)16-17-3-7-21-24(14-17)31-27(35)22-2-1-9-29-25(21)22/h3,6-8,14-15,18,29H,1-2,4-5,9-13,16H2,(H,30,34)(H,31,35)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.87	n/a	n/a	n/a	n/a	n/a	n/a
Je Il Pharmaceutical Co., Ltd. US Patent					Assay Description The tankyrase-1 or tankyrase-2 enzyme inhibitory activities of the compounds of the present invention were assayed in the following manner by use of ...				US Patent US10464919 (2019) BindingDB Entry DOI: 10.7270/Q2736T8M
					More data for this Ligand-Target Pair
Non-receptor tyrosine-protein kinase TNK1 (Homo sapiens (Human))	BDBM419740 (US10464919, Example 78) Show SMILES Fc1cc(ccc1C(=O)NC1CC1)N1CCN(Cc2ccc3c4NCCCc4c(=O)[nH]c3c2)CC1 Show InChI InChI=1S/C27H30FN5O2/c28-23-15-19(6-8-20(23)26(34)30-18-4-5-18)33-12-10-32(11-13-33)16-17-3-7-21-24(14-17)31-27(35)22-2-1-9-29-25(21)22/h3,6-8,14-15,18,29H,1-2,4-5,9-13,16H2,(H,30,34)(H,31,35)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Je Il Pharmaceutical Co., Ltd. US Patent					Assay Description The tankyrase-1 or tankyrase-2 enzyme inhibitory activities of the compounds of the present invention were assayed in the following manner by use of ...				US Patent US10464919 (2019) BindingDB Entry DOI: 10.7270/Q2736T8M
					More data for this Ligand-Target Pair