null

SMILES: CN[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N1C[C@@H](F)C[C@H]1Cc1c([nH]c2cc(F)ccc12)-c1nc2cc(F)ccc2n1C[C@@H]1C[C@H](F)CN1C(=O)[C@@H](NC(=O)[C@H](C)NC)C(C)C

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 422063   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Baculoviral IAP repeat-containing protein 2 [253-363] (Homo sapiens (Human))	BDBM422063 (US10508103, Embodiment 16) Show SMILES CN[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N1C[C@@H](F)C[C@H]1Cc1c([nH]c2cc(F)ccc12)-c1nc2cc(F)ccc2n1C[C@@H]1C[C@H](F)CN1C(=O)[C@@H](NC(=O)[C@H](C)NC)C(C)C |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
MEDSHINE DISCOVERY INC. US Patent					Assay Description 1) Affinity of compounds listed in table to cIAP1-BIR3, Ciap2-BIR3, XIAP-BIR3 was tested referring to Nikolovska-Colesks, Z. et.Al. (Analytical Bioch...				US Patent US10508103 (2019) BindingDB Entry DOI: 10.7270/Q25141MH
					More data for this Ligand-Target Pair
Tumor necrosis factor (Homo sapiens (Human))	BDBM422063 (US10508103, Embodiment 16) Show SMILES CN[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N1C[C@@H](F)C[C@H]1Cc1c([nH]c2cc(F)ccc12)-c1nc2cc(F)ccc2n1C[C@@H]1C[C@H](F)CN1C(=O)[C@@H](NC(=O)[C@H](C)NC)C(C)C |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	<10	n/a	n/a	n/a	n/a
MEDSHINE DISCOVERY INC. US Patent					Assay Description First day:Dilution of Compounds: 1) tested compounds were added into DMSO to give parent liquor (10 mM); 2) reference compound Birinapant (32 &...				US Patent US10508103 (2019) BindingDB Entry DOI: 10.7270/Q25141MH
					More data for this Ligand-Target Pair
E3 ubiquitin-protein ligase XIAP [241-356] (Homo sapiens (Human))	BDBM422063 (US10508103, Embodiment 16) Show SMILES CN[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N1C[C@@H](F)C[C@H]1Cc1c([nH]c2cc(F)ccc12)-c1nc2cc(F)ccc2n1C[C@@H]1C[C@H](F)CN1C(=O)[C@@H](NC(=O)[C@H](C)NC)C(C)C |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
MEDSHINE DISCOVERY INC. US Patent					Assay Description 1) Affinity of compounds listed in table to cIAP1-BIR3, Ciap2-BIR3, XIAP-BIR3 was tested referring to Nikolovska-Colesks, Z. et.Al. (Analytical Bioch...				US Patent US10508103 (2019) BindingDB Entry DOI: 10.7270/Q25141MH
					More data for this Ligand-Target Pair
Baculoviral IAP repeat-containing protein 3 [238-349] (Homo sapiens (Human))	BDBM422063 (US10508103, Embodiment 16) Show SMILES CN[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N1C[C@@H](F)C[C@H]1Cc1c([nH]c2cc(F)ccc12)-c1nc2cc(F)ccc2n1C[C@@H]1C[C@H](F)CN1C(=O)[C@@H](NC(=O)[C@H](C)NC)C(C)C |r| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
MEDSHINE DISCOVERY INC. US Patent					Assay Description 1) Affinity of compounds listed in table to cIAP1-BIR3, Ciap2-BIR3, XIAP-BIR3 was tested referring to Nikolovska-Colesks, Z. et.Al. (Analytical Bioch...				US Patent US10508103 (2019) BindingDB Entry DOI: 10.7270/Q25141MH
					More data for this Ligand-Target Pair