BDBM42286 5-[2-(2,5-dimethoxyanilino)-1,3-thiazol-4-yl]-4-methyl-1,3-thiazol-2-amine::5-[2-(2,5-dimethoxyanilino)-4-thiazolyl]-4-methyl-2-thiazolamine::5-[2-[(2,5-dimethoxyphenyl)amino]-1,3-thiazol-4-yl]-4-methyl-1,3-thiazol-2-amine::MLS000034309::N*2*-(2,5-Dimethoxy-phenyl)-4'-methyl-[4,5']bithiazolyl-2,2'-diamine::SMR000011634::[4-(2-amino-4-methyl-thiazol-5-yl)thiazol-2-yl]-(2,5-dimethoxyphenyl)amine::cid_654122

SMILES: COc1ccc(OC)c(Nc2nc(cs2)-c2sc(N)nc2C)c1

InChI Key: InChIKey=HRKHVNBKAKFINO-UHFFFAOYSA-N

Data: 1 IC50  2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 42286   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lysosomal acid glucosylceramidase (Homo sapiens (Human))	BDBM42286 (5-[2-(2,5-dimethoxyanilino)-1,3-thiazol-4-yl]-4-me...) Show SMILES COc1ccc(OC)c(Nc2nc(cs2)-c2sc(N)nc2C)c1 Show InChI InChI=1S/C15H16N4O2S2/c1-8-13(23-14(16)17-8)11-7-22-15(19-11)18-10-6-9(20-2)4-5-12(10)21-3/h4-7H,1-3H3,(H2,16,17)(H,18,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay					Assay Description Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assay ...				PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q23J3BC8
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase TAO2 (Rattus norvegicus)	BDBM42286 (5-[2-(2,5-dimethoxyanilino)-1,3-thiazol-4-yl]-4-me...) Show SMILES COc1ccc(OC)c(Nc2nc(cs2)-c2sc(N)nc2C)c1 Show InChI InChI=1S/C15H16N4O2S2/c1-8-13(23-14(16)17-8)11-7-22-15(19-11)18-10-6-9(20-2)4-5-12(10)21-3/h4-7H,1-3H3,(H2,16,17)(H,18,19)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Southwestern Medical Center Curated by ChEMBL					Assay Description Inhibition of rat TAOK2 (1 to 320 residues) expressed in Baculovirus/insect cell expression system assessed as remaining activity using MBP as substr...				Bioorg Med Chem Lett 26: 3923-7 (2016) Article DOI: 10.1016/j.bmcl.2016.07.016
					More data for this Ligand-Target Pair
glutathione S-transferase (Homo sapiens (Human))	BDBM42286 (5-[2-(2,5-dimethoxyanilino)-1,3-thiazol-4-yl]-4-me...) Show SMILES COc1ccc(OC)c(Nc2nc(cs2)-c2sc(N)nc2C)c1 Show InChI InChI=1S/C15H16N4O2S2/c1-8-13(23-14(16)17-8)11-7-22-15(19-11)18-10-6-9(20-2)4-5-12(10)21-3/h4-7H,1-3H3,(H2,16,17)(H,18,19)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	2.69E+4	n/a	n/a	n/a	n/a
NMMLSC Curated by PubChem BioAssay					Assay Description University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-re...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2ZC8184
					More data for this Ligand-Target Pair