null

SMILES: COc1cc(CO)c(cc1Cl)-c1cn2ccc(N[C@H]3CC[C@@H](CC3)NC(=O)CO)cc2n1

InChI Key: InChIKey=IVHZDNBMGXJSED-WKILWMFISA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 423091   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone-lysine N-methyltransferase SUV39H2 (Homo sapiens (Human))	BDBM423091 ((methyl(4-((2-(5-chloro-2,4- dimethoxyphenyl)imida...) Show SMILES COc1cc(CO)c(cc1Cl)-c1cn2ccc(N[C@H]3CC[C@@H](CC3)NC(=O)CO)cc2n1 |r,wU:21.25,wD:18.18,(-10.06,-.19,;-9.29,1.14,;-7.75,1.14,;-6.98,-.19,;-5.44,-.19,;-4.67,-1.53,;-5.44,-2.86,;-4.67,1.14,;-5.44,2.48,;-6.98,2.48,;-7.75,3.81,;-3.13,1.14,;-2.22,-.1,;-.76,.37,;.57,-.4,;1.91,.37,;1.91,1.91,;3.24,2.68,;4.58,1.91,;4.58,.37,;5.91,-.4,;7.24,.37,;7.24,1.91,;5.91,2.68,;8.58,-.4,;8.58,-1.94,;7.24,-2.71,;9.91,-2.71,;9.91,-4.25,;.57,2.68,;-.76,1.91,;-2.22,2.39,)| Show InChI InChI=1S/C23H27ClN4O4/c1-32-21-8-14(12-29)18(10-19(21)24)20-11-28-7-6-17(9-22(28)27-20)25-15-2-4-16(5-3-15)26-23(31)13-30/h6-11,15-16,25,29-30H,2-5,12-13H2,1H3,(H,26,31)/t15-,16-	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.24	n/a	n/a	n/a	n/a	n/a	n/a
ONCOTHERAPY SCIENCE, INC. US Patent					Assay Description Assay buffer (4 μL) was added into all the wells, including test compound and control wells (except for Sinefungin control wells), using the Mul...				US Patent US10508109 (2019) BindingDB Entry DOI: 10.7270/Q2H997K9
					More data for this Ligand-Target Pair